STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG7099B-block_TFIIIC domain-containing protein; It is involved in the biological process described with: transcription initiation from RNA polymerase III promoter; 5S class rRNA transcription by RNA polymerase III. (1906 aa)    
Predicted Functional Partners:
CG8950
LD44919p; It is involved in the biological process described with: transcription by RNA polymerase III.
   
 0.977
l(2)37Cd
Lethal (2) 37Cd; It is involved in the biological process described with: transcription initiation from RNA polymerase III promoter.
   
 0.973
CG42588
Uncharacterized protein, isoform A; It is involved in the biological process described with: transcription by RNA polymerase III.
   
 0.924
CG42516
LD18062p1; It is involved in the biological process described with: transcription by RNA polymerase III.
    
 0.900
Brf
Brf, isoform A; Brf (Brf) encodes a transcription factor binding protein involved in transcription mediated by RNA polymerase III.
   
 
 0.863
Bdp1
B double prime 1 (Bdp1) encodes a transcription factor involved in snRNA gene transcription.
   
 0.836
CG17189
IP09938p.
      
 0.790
BEAF-32
Boundary element-associated factor of 32kD (BEAF-32) encodes a DNA-binding protein with binding sites near transcription start sites. Its roles include chromatin domain insulator function, gene regulation and genome organization.
    
 
 0.705
barr
Condensin complex subunit 2; Barren (barr) encodes a chromatin binding protein involved in chromatin condensation. It regulates Malpighian tubule development and epithelial morphogenesis.
   
  
 0.694
dwg
Deformed wings (dwg) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in regulatory regions (predominantly promoters). dwg product binding site was found in the insulator encoded by scs, and its functions include enhancer blocking, support of distant interactions and recruitment of transcription factors.
   
 
 0.680
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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