Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG10859GH14707p; Dynein light chain binding; dynein heavy chain binding. It is involved in the biological process described with: microtubule-based movement; cilium movement; outer dynein arm assembly. (627 aa)    
Predicted Functional Partners:
CG9313
Uncharacterized protein, isoform B; Dynein light chain binding; dynein heavy chain binding. It is involved in the biological process described with: cilium movement; outer dynein arm assembly; microtubule-based movement; sensory perception of sound.
  
 0.992
CG9492
Uncharacterized protein, isoform G; Dynein intermediate chain binding; ATP-dependent microtubule motor activity, minus-end-directed; ATP binding; dynein light intermediate chain binding. It is involved in the biological process described with: cilium movement; outer dynein arm assembly; microtubule-based movement; sensory perception of sound.
  
 0.966
CG8800
Uncharacterized protein; Motor activity; alpha-tubulin binding; dynein heavy chain binding. It is involved in the biological process described with: outer dynein arm assembly.
  
 
 0.959
kl-3
Male fertility factor kl3 (kl-3) encodes a dynein heavy chain that is a component of a microtubule motor complex. This motor activity is essential only for spermatogenesis. Lack of kl-3 results in loss of the axonemal out dynein arms in the spermatid tail.
  
 0.952
Dnali1
Putative inner dynein arm light chain, axonemal; May play a dynamic role in flagellar motility.
  
 0.946
CG3339
Uncharacterized protein; Dynein intermediate chain binding; ATP-dependent microtubule motor activity, minus-end-directed; dynein light intermediate chain binding; ATP binding. It is involved in the biological process described with: cilium movement; microtubule-based movement.
  
 
 0.943
Dhc93AB
Dynein heavy chain at 93AB (Dhc93AB) encodes a motor protein involved in hearing.
  
 0.937
Dnai2
Dynein, axonemal, intermediate chain 2 (Dnai2) encodes a subunit of the axonemal dynein complex. It is involved in the perception of sound and sperm competititon.
  
  
0.919
CG1571
FI19907p1; Dynein heavy chain binding; dynein light chain binding. It is involved in the biological process described with: microtubule-based movement; outer dynein arm assembly; cilium movement.
  
 
0.914
Dic61B
Dynein intermediate chain at 61B (Dic61B) encodes an axonemal dynein intermediate chain protein expressed specifically in male germ cells. It is required for the development and precise assembly of sperm axonemes, thus it is essential for male fertility.
  
 
 0.882
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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