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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG10859GH14707p; Dynein light chain binding; dynein heavy chain binding. It is involved in the biological process described with: microtubule-based movement; cilium movement; outer dynein arm assembly. (627 aa)    
Predicted Functional Partners:
CG9313
Uncharacterized protein, isoform B; Dynein light chain binding; dynein heavy chain binding. It is involved in the biological process described with: cilium movement; outer dynein arm assembly; microtubule-based movement; sensory perception of sound.
  
 
 0.956
Dic61B
Dynein intermediate chain at 61B (Dic61B) encodes an axonemal dynein intermediate chain protein expressed specifically in male germ cells. It is required for the development and precise assembly of sperm axonemes, thus it is essential for male fertility.
  
 
 0.885
kl-3
Male fertility factor kl3 (kl-3) encodes a dynein heavy chain that is a component of a microtubule motor complex. This motor activity is essential only for spermatogenesis. Lack of kl-3 results in loss of the axonemal out dynein arms in the spermatid tail.
  
 0.879
Dnali1
Putative inner dynein arm light chain, axonemal; May play a dynamic role in flagellar motility.
  
 
 0.871
CG8800
Uncharacterized protein; Motor activity; alpha-tubulin binding; dynein heavy chain binding. It is involved in the biological process described with: outer dynein arm assembly.
  
 
 0.870
kl-5
Male fertility factor kl5; ATP binding; microtubule motor activity. It is involved in the biological process described with: microtubule-based movement.
  
 0.853
CG3339
Uncharacterized protein; Dynein intermediate chain binding; ATP-dependent microtubule motor activity, minus-end-directed; dynein light intermediate chain binding; ATP binding. It is involved in the biological process described with: cilium movement; microtubule-based movement.
  
 0.846
Dhc93AB
Dynein heavy chain at 93AB (Dhc93AB) encodes a motor protein involved in hearing.
  
 0.833
Dhc36C
Dynein heavy chain at 36C (Dhc36C) encodes a motor protein involved in hearing.
  
 0.819
robl
Roadblock (robl) encodes a dynein-associated protein involved in intracellular transport mediated by Dynein. It contributes to dendrite morphogenesis and mushroom body development.
   
 0.780
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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