STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AcypAcylphosphatase-1; Acylphosphatase activity. (120 aa)    
Predicted Functional Partners:
AcCoAS
Acetyl-coenzyme A synthetase; Activates acetate so that it can be used for lipid synthesis or for energy generation; Belongs to the ATP-dependent AMP-binding enzyme family.
     
  0.900
CG17030
AT26201p; Ubiquitin protein ligase binding; ubiquitin conjugating enzyme activity; ubiquitin-protein transferase activity. It is involved in the biological process described with: protein polyubiquitination; ubiquitin-dependent protein catabolic process.
   
    0.669
CG7214
HL02931p.
   
  
 0.666
Aldh7A1
Aldehyde dehydrogenase 7 family member A1; Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: oxidation-reduction process.
     
 0.655
Aldh
Aldehyde dehydrogenase (Aldh) encodes an NAD[+] dependent mitochondrial aldehyde dehydrogenase. Its functions include detoxifying endogenous aldehydes generated by lipid peroxidation, and detoxifying acetaldehyde derived from dietary ethanol.
     
  0.650
CG31075
Uncharacterized protein, isoform B; Aldehyde dehydrogenase (NAD+) activity. It is involved in the biological process described with: oxidation-reduction process; pyruvate metabolic process.
     
  0.650
CG17648
GEO08907p1.
   
    0.626
CG30178
Uncharacterized protein; Transcription coregulator activity.
   
    0.559
retinin
Retinin; Structural constituent of eye lens.
      
 0.528
CG6765
Uncharacterized protein, isoform A; Nucleic acid binding. It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
      
 0.523
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.