STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Adat1tRNA-specific adenosine deaminase 1; Specifically deaminates adenosine-37 to inosine in tRNA-Ala. (394 aa)    
Predicted Functional Partners:
CG10927
LD07624p; tRNA-specific adenosine-34 deaminase activity. It is involved in the biological process described with: tRNA wobble adenosine to inosine editing.
   
  
 0.644
LysRS
Lysine--tRNA ligase; tRNA binding; ATP binding; lysine-tRNA ligase activity. It is involved in the biological process described with: lysyl-tRNA aminoacylation.
 
    
 0.592
Nsun2
tRNA (cytosine(34)-C(5))-methyltransferase; RNA methyltransferase that methylates tRNAs. Methylates cytosine to 5-methylcytosine (m5C) at position 34 of intron-containing tRNA(Leu)(CAA) precursors. Required for short-term memory.
      
 0.547
Mt2
Methyltransferase 2 (Mt2) encodes a (cytosine-5) tRNA methyltransferase. The modification protects tRNAs against endonucleolytic cleavage and contributes to stress resistance, protein translation and small RNA-mediated gene regulation; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
   
  
 0.540
Adgf-B
Adenosine deaminase-related growth factor B; Adenosine deaminase activity. It is involved in the biological process described with: inosine biosynthetic process; adenosine catabolic process.
      
 0.536
Adgf-E
Adenosine deaminase-related growth factor E; It is involved in the biological process described with: inosine biosynthetic process.
      
 0.536
PNPase
Polynucleotide phosphorylase (PNPase) encodes an enzyme involved in the regulation of mitochondrial mRNA stability.
    
 
 0.529
Ada
Adenosine deaminase-like protein; Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A); Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
   
  
 0.518
Adgf-D
Adenosine deaminase-related growth factor D (Adgf-D) encodes an adenosine deaminase involved in cell proliferation.
      
 0.516
Nph
Nucleophosmin, isoform A; Nucleophosmin (Nph) encodes a histone binding protein involved in chromatin remodeling and sperm chromatin decondensation.
      
 0.493
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.