STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NimB2Nimrod B2; It is involved in the biological process described with: defense response to bacterium; mesoderm development. (421 aa)    
Predicted Functional Partners:
CG33056
GH17661p; ADP-ribosylglutamate hydrolase activity; purine nucleoside binding. It is involved in the biological process described with: peptidyl-glutamate ADP-deribosylation; purine nucleoside metabolic process.
   
  
 0.663
CG10527
Uncharacterized protein.
   
   0.535
CG7744
FI17509p1; Lamin binding; actin filament binding. It is involved in the biological process described with: nuclear migration along microtubule.
      
 0.521
Spn43Ab
Serpin 43Ab; Serine-type endopeptidase inhibitor activity. It is involved in the biological process described with: negative regulation of endopeptidase activity; multicellular organism reproduction; Belongs to the serpin family.
   
  
 0.521
Sr-CIII
Scavenger receptor class C, type III.
   
 
 0.509
IM33
Immune induced molecule 33 (IM33) encodes a protein that belongs to a class of small secreted peptides released in the hemolymph upon systemic microbial infection.
   
  
 0.497
CG2656
GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
   
  
 0.493
grsm
Granny smith (grsm) encodes a member of the M17 family of leucine aminopeptidases, a family of proteases broadly involved in a number of cellular processes. High throughput transcriptomic and proteomic analyses have implicated the product of grsm in the regulation of immune-, nervous- and immune-related processes.
      
 0.493
NimB3
GEO11169p1; It is involved in the biological process described with: defense response to bacterium.
   
  
0.483
yellow-f2
L-dopachrome tautomerase yellow-f2; Tautomerization of L-dopachrome with decarboxylation to give 5,6-dihydroxyindole (DHI). Also catalyzes the tautomerization of the methyl ester of L-dopachrome and dopamine chrome. May play a role in melanization reactions during late pupal and adult stages. Belongs to the major royal jelly protein family.
   
  
 0.479
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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