STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG15270Anoctamin; Intracellular calcium activated chloride channel activity; calcium activated cation channel activity. It is involved in the biological process described with: chloride transport; cation transport; transmembrane transport. (1338 aa)    
Predicted Functional Partners:
Liprin-gamma
Liprin-gamma, isoform C; Liprin-gamma (Liprin-gamma) encodes an adaptor protein that counteracts the functions of the product of Liprin-alpha in photoreceptor axon targeting and the product of Liprin-beta in neuromuscular junction development, potentially through competition for binding partners.
   
    0.729
tipE
Protein tipE; Enhances para sodium channel function. Required during pupal development to rescue adult paralysis and also protects adult flies against heat-induced lethality.
   
    0.718
CG4467
Uncharacterized protein, isoform B; Metalloaminopeptidase activity; zinc ion binding; peptide binding. It is involved in the biological process described with: peptide catabolic process; proteolysis.
   
  
 0.704
CG13175
GEO13458p1.
      
 0.679
CG30159
GH17623p.
      
 0.679
Tsp42Ea
Tetraspanin.
      
 0.669
CG5521
Probable Rho GTPase-activating protein CG5521; GTPase activator activity. It is involved in the biological process described with: regulation of small GTPase mediated signal transduction; positive regulation of GTPase activity.
      
 0.669
CG43980
Uncharacterized protein, isoform C; Protein heterodimerization activity.
      
 0.668
CG10283
Uncharacterized protein, isoform C; Ubiquitin protein ligase binding.
      
 0.664
CG7744
FI17509p1; Lamin binding; actin filament binding. It is involved in the biological process described with: nuclear migration along microtubule.
      
 0.662
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.