| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG14322 | CG4049 | FBpp0303764 | FBpp0072192 | Uncharacterized protein, isoform B; Ubiquitin binding. It is involved in the biological process described with: protein polyubiquitination. | Uncharacterized protein; ATP binding. | 0.928 |
| CG14322 | CG5886 | FBpp0303764 | FBpp0084281 | Uncharacterized protein, isoform B; Ubiquitin binding. It is involved in the biological process described with: protein polyubiquitination. | GH01188p; Syntaxin binding. | 0.973 |
| CG14322 | CG9799 | FBpp0303764 | FBpp0082231 | Uncharacterized protein, isoform B; Ubiquitin binding. It is involved in the biological process described with: protein polyubiquitination. | LD47749p; It is involved in the biological process described with: rRNA processing. | 0.835 |
| CG14322 | heix | FBpp0303764 | FBpp0080409 | Uncharacterized protein, isoform B; Ubiquitin binding. It is involved in the biological process described with: protein polyubiquitination. | UbiA prenyltransferase domain-containing protein 1 homolog; Prenyltransferase that mediates the formation of menaquinone- 4 (MK-4), a vitamin K2 isoform, thereby acting as a mitochondrial electron carrier. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. MK-4 acts as a membrane electron carrier downstream of a electron transport chain complex, improving mitochondrial oxygen consumption. | 0.840 |
| CG4049 | CG14322 | FBpp0072192 | FBpp0303764 | Uncharacterized protein; ATP binding. | Uncharacterized protein, isoform B; Ubiquitin binding. It is involved in the biological process described with: protein polyubiquitination. | 0.928 |
| CG4049 | CG5886 | FBpp0072192 | FBpp0084281 | Uncharacterized protein; ATP binding. | GH01188p; Syntaxin binding. | 0.915 |
| CG4049 | CG9799 | FBpp0072192 | FBpp0082231 | Uncharacterized protein; ATP binding. | LD47749p; It is involved in the biological process described with: rRNA processing. | 0.616 |
| CG4049 | heix | FBpp0072192 | FBpp0080409 | Uncharacterized protein; ATP binding. | UbiA prenyltransferase domain-containing protein 1 homolog; Prenyltransferase that mediates the formation of menaquinone- 4 (MK-4), a vitamin K2 isoform, thereby acting as a mitochondrial electron carrier. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. MK-4 acts as a membrane electron carrier downstream of a electron transport chain complex, improving mitochondrial oxygen consumption. | 0.630 |
| CG5886 | CG14322 | FBpp0084281 | FBpp0303764 | GH01188p; Syntaxin binding. | Uncharacterized protein, isoform B; Ubiquitin binding. It is involved in the biological process described with: protein polyubiquitination. | 0.973 |
| CG5886 | CG4049 | FBpp0084281 | FBpp0072192 | GH01188p; Syntaxin binding. | Uncharacterized protein; ATP binding. | 0.915 |
| CG5886 | CG9799 | FBpp0084281 | FBpp0082231 | GH01188p; Syntaxin binding. | LD47749p; It is involved in the biological process described with: rRNA processing. | 0.835 |
| CG5886 | heix | FBpp0084281 | FBpp0080409 | GH01188p; Syntaxin binding. | UbiA prenyltransferase domain-containing protein 1 homolog; Prenyltransferase that mediates the formation of menaquinone- 4 (MK-4), a vitamin K2 isoform, thereby acting as a mitochondrial electron carrier. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. MK-4 acts as a membrane electron carrier downstream of a electron transport chain complex, improving mitochondrial oxygen consumption. | 0.838 |
| CG8311 | heix | FBpp0086267 | FBpp0080409 | Uncharacterized protein; Dolichol kinase activity. It is involved in the biological process described with: dolichyl monophosphate biosynthetic process. | UbiA prenyltransferase domain-containing protein 1 homolog; Prenyltransferase that mediates the formation of menaquinone- 4 (MK-4), a vitamin K2 isoform, thereby acting as a mitochondrial electron carrier. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. MK-4 acts as a membrane electron carrier downstream of a electron transport chain complex, improving mitochondrial oxygen consumption. | 0.620 |
| CG9799 | CG14322 | FBpp0082231 | FBpp0303764 | LD47749p; It is involved in the biological process described with: rRNA processing. | Uncharacterized protein, isoform B; Ubiquitin binding. It is involved in the biological process described with: protein polyubiquitination. | 0.835 |
| CG9799 | CG4049 | FBpp0082231 | FBpp0072192 | LD47749p; It is involved in the biological process described with: rRNA processing. | Uncharacterized protein; ATP binding. | 0.616 |
| CG9799 | CG5886 | FBpp0082231 | FBpp0084281 | LD47749p; It is involved in the biological process described with: rRNA processing. | GH01188p; Syntaxin binding. | 0.835 |
| CG9799 | heix | FBpp0082231 | FBpp0080409 | LD47749p; It is involved in the biological process described with: rRNA processing. | UbiA prenyltransferase domain-containing protein 1 homolog; Prenyltransferase that mediates the formation of menaquinone- 4 (MK-4), a vitamin K2 isoform, thereby acting as a mitochondrial electron carrier. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. MK-4 acts as a membrane electron carrier downstream of a electron transport chain complex, improving mitochondrial oxygen consumption. | 0.791 |
| Coq2 | Hmgcr | FBpp0081347 | FBpp0083842 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Synthesis of mevalonate for the production of non-sterol isoprenoids, which are essential for growth differentiation. Provides spatial information during embryogenesis to guide migrating primordial germ cells (the pole cells) from the ectoderm to the mesoderm. Also required for association of the pole cells with the gonadal mesoderm. Belongs to the HMG-CoA reductase family. | 0.754 |
| Coq2 | heix | FBpp0081347 | FBpp0080409 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | UbiA prenyltransferase domain-containing protein 1 homolog; Prenyltransferase that mediates the formation of menaquinone- 4 (MK-4), a vitamin K2 isoform, thereby acting as a mitochondrial electron carrier. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. MK-4 acts as a membrane electron carrier downstream of a electron transport chain complex, improving mitochondrial oxygen consumption. | 0.777 |
| Coq2 | qm | FBpp0081347 | FBpp0291255 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate; Belongs to the UbiA prenyltransferase family. | Quemao, isoform A; Quemao (qm) encodes the ortholog of human geranylgeranyl pyrophosphate synthase (GGPS1), which catalyses protein prenylation and thereby facilitates membrane targeting of proteins. The qm product contributes to heart formation, germ cell migration, and maintenance of plasma membrane integrity in growing oocytes. | 0.662 |