Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Idgf2Chitinase-like protein Idgf2; Cooperates with insulin-like peptides to stimulate the proliferation, polarization and motility of imaginal disk cells. May act by stabilizing the binding of insulin-like peptides to its receptor through a simultaneous interaction with both molecules to form a multiprotein signaling complex; Belongs to the glycosyl hydrolase 18 family. IDGF subfamily. (440 aa)    
Predicted Functional Partners:
CG15202
Uncharacterized protein, isoform A.
   
  
 0.611
CG32549
Uncharacterized protein, isoform G; 5'-nucleotidase activity.
   
  
 0.595
Idgf1
Chitinase-like protein Idgf1; Cooperates with insulin-like peptides to stimulate the proliferation, polarization and motility of imaginal disk cells. May act by stabilizing the binding of insulin-like peptides to its receptor through a simultaneous interaction with both molecules to form a multiprotein signaling complex.
  
  
0.550
CG5254
EG:BACR19J1.2 protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
  
 0.486
CG13676
Uncharacterized protein, isoform A; Chitin binding. It is involved in the biological process described with: chitin metabolic process.
      
 0.465
Idgf6
Imaginal disc growth factor 6 (Idgf6) is one of six genes in the IDGF family, which evolved from chitinases that lost their enzymatic activity. Idgf6 encodes a secreted protein that is highly expressed in larval fat body and adult head. Idgf6 product is involved in molting and egg chamber tube morphogenesis.
  
  
0.425
Cht12
Chitinase 12 (Cht12) encodes an enzyme involved in cuticle development, ecdysis and wound healing; Belongs to the glycosyl hydrolase 18 family.
  
   
0.407
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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