STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Idgf3Chitinase-like protein Idgf3; Cooperates with insulin-like peptides to stimulate the proliferation, polarization and motility of imaginal disk cells. May act by stabilizing the binding of insulin-like peptides to its receptor through a simultaneous interaction with both molecules to form a multiprotein signaling complex; Belongs to the glycosyl hydrolase 18 family. IDGF subfamily. (441 aa)    
Predicted Functional Partners:
CG15202
Uncharacterized protein, isoform A.
      
 0.660
CG9706
Uncharacterized protein, isoform C; Solute:proton symporter activity; acetyl-CoA transmembrane transporter activity.
   
  
 0.604
obst-A
Obstructor-A, isoform A; obstructor-A (obst-A) encodes a protein that forms a core complex with chitin and the chitin modifying proteins encoded by serp and knk. This complex is required for assembly, maturation and preservation of the chitinous cuticles at the end of embryogenesis and probably throughout larval development.
      
 0.602
DppIII
Dipeptidyl peptidase 3; Degrades neuropeptide proctolin (RYLPT) by cleavage between Tyr and Leu residues; Belongs to the peptidase M49 family.
      
 0.546
CG17739
GH02025p; Serine-type endopeptidase inhibitor activity. It is involved in the biological process described with: cell adhesion.
   
  
 0.530
cmb
Combover, isoform A; Combover (cmb) encodes an in vitro substrate of the product of Rho1 that physically interacts with the planar cell polarity (PCP) effector encoded by mwh. It contributes to PCP during wing hair formation.
      
 0.515
CG9705
Cold shock domain-containing protein CG9705; mRNA 3'-UTR binding. It is involved in the biological process described with: regulation of mRNA stability; dendrite morphogenesis.
      
 0.461
Cht12
Chitinase 12 (Cht12) encodes an enzyme involved in cuticle development, ecdysis and wound healing; Belongs to the glycosyl hydrolase 18 family.
  
   
0.433
ng2
annotation not available
   
  
 0.431
Acp26Ab
Accessory gland protein 26Ab (Acp26Ab) encodes a peptide that is produced by male accessory glands and transferred to females during mating.
      
 0.420
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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