STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdyO-acyltransferase; Midway (mdy) encodes an acyl coenzyme A: diacylglycerol acyltransferase that functions in the formation of triglycerides. Lack of mdy leads to female sterility and impaired fat metabolism in larvae and adults. (565 aa)    
Predicted Functional Partners:
Dgat2
Diacylglycerol O-acyltransferase activity; O-acyltransferase activity. It is involved in the biological process described with: lipid droplet organization; mesoderm development; lipid metabolic process; triglyceride biosynthetic process.
   
 0.994
Lpin
Lipin, isoform A; Lipin (Lpin) encodes a protein that plays a central role in fat body function and energy metabolism. It works as a phosphatidate phosphatase required for normal insulin pathway signaling.
    
 0.987
CG1941
RE04845p; O-acyltransferase activity; diacylglycerol O-acyltransferase activity. It is involved in the biological process described with: lipid metabolic process; triglyceride biosynthetic process.
   
 0.975
CG1946
IP08359p; O-acyltransferase activity; diacylglycerol O-acyltransferase activity. It is involved in the biological process described with: triglyceride biosynthetic process; lipid metabolic process.
    
 0.972
CG11437
RE35159p; Phosphatidate phosphatase activity; phosphatase activity; lipid phosphatase activity. It is involved in the biological process described with: phospholipid dephosphorylation; phospholipid metabolic process; signal transduction.
    
 0.942
CG11438
RH32172p; Phosphatidate phosphatase activity; phosphatase activity; lipid phosphatase activity. It is involved in the biological process described with: phospholipid dephosphorylation; phospholipid metabolic process; signal transduction.
   
 0.942
CG11425
GH04282p; Lipid phosphatase activity; phosphatidate phosphatase activity; phosphatase activity. It is involved in the biological process described with: phospholipid dephosphorylation; phospholipid metabolic process; signal transduction.
    
 0.940
frj
Farjavit, isoform A; Farjavit (frj) encodes a lysophospholipid acyltransferase that preferentially adds arachidonic acid to lysophosphatidylinositol; Belongs to the membrane-bound acyltransferase family.
   
 
 0.938
CG11426
FI20175p1; Phosphatidate phosphatase activity; phosphatase activity; lipid phosphatase activity. It is involved in the biological process described with: signal transduction; phototransduction; phospholipid metabolic process; phospholipid dephosphorylation.
    
 0.933
CG10672
SD02021p; Carbonyl reductase (NADPH) activity; 3-keto sterol reductase activity; oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor.
     
 0.930
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.