| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Aatf | Dhx15 | FBpp0078929 | FBpp0088040 | Protein Aatf; Apoptosis antagonizing transcription factor (Aatf) encodes a transcription factor that is a target of the kinases encoded by tefu and lok. It is involved in the control of the cell cycle, DNA damage response, and regulation of apoptosis. | DEAH-box helicase 15, isoform A; RNA helicase activity; RNA binding; ATP binding. It is involved in the biological process described with: positive regulation of p38MAPK cascade; mRNA splicing, via spliceosome. | 0.754 |
| Aatf | cass | FBpp0078929 | FBpp0080554 | Protein Aatf; Apoptosis antagonizing transcription factor (Aatf) encodes a transcription factor that is a target of the kinases encoded by tefu and lok. It is involved in the control of the cell cycle, DNA damage response, and regulation of apoptosis. | Apoptosis inhibitor 5 homolog; Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis. | 0.493 |
| Acn | cass | FBpp0307803 | FBpp0080554 | Acinus, isoform A; Acinus (Acn) encodes nuclear protein that, together with the products of a Bin1 and RnpS1, forms the ASAP complex that contributes to the regulation of alternative splicing. The Acn protein also functions in basal, starvation-independent autophagy. | Apoptosis inhibitor 5 homolog; Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis. | 0.552 |
| Acn | scaf6 | FBpp0307803 | FBpp0075048 | Acinus, isoform A; Acinus (Acn) encodes nuclear protein that, together with the products of a Bin1 and RnpS1, forms the ASAP complex that contributes to the regulation of alternative splicing. The Acn protein also functions in basal, starvation-independent autophagy. | SR-related CTD associated factor 6, isoform A; RNA binding. It is involved in the biological process described with: cellular calcium ion homeostasis; RNA processing. | 0.507 |
| BI-1 | cass | FBpp0076434 | FBpp0080554 | Bax inhibitor 1; Suppressor of apoptosis (By similarity). Modulates unfolded protein response signaling. Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation. | Apoptosis inhibitor 5 homolog; Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis. | 0.521 |
| CG5110 | cass | FBpp0297292 | FBpp0080554 | Ragulator complex protein LAMTOR3 homolog; CG5110 encodes a scaffold protein that associates with the MAP kinase kinase and the MAP kinase encoded by Mekk1 and rl respectively. It regulates the vein promoting function of rl during wing imaginal disc development in third instar larvae; Belongs to the LAMTOR3 family. | Apoptosis inhibitor 5 homolog; Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis. | 0.679 |
| CG5110 | fws | FBpp0297292 | FBpp0080553 | Ragulator complex protein LAMTOR3 homolog; CG5110 encodes a scaffold protein that associates with the MAP kinase kinase and the MAP kinase encoded by Mekk1 and rl respectively. It regulates the vein promoting function of rl during wing imaginal disc development in third instar larvae; Belongs to the LAMTOR3 family. | Conserved oligomeric Golgi complex subunit 5; Four way stop (fws) encodes a protein localised to the Golgi apparatus and involved in several aspects of spermatogenesis. Loss of function of fws causes failure of cleavage furrow ingression in dividing spermatocytes, as well as failure of cell elongation and disruption of the Golgi-based acroblast during spermatid differentiation. | 0.792 |
| Dhx15 | Aatf | FBpp0088040 | FBpp0078929 | DEAH-box helicase 15, isoform A; RNA helicase activity; RNA binding; ATP binding. It is involved in the biological process described with: positive regulation of p38MAPK cascade; mRNA splicing, via spliceosome. | Protein Aatf; Apoptosis antagonizing transcription factor (Aatf) encodes a transcription factor that is a target of the kinases encoded by tefu and lok. It is involved in the control of the cell cycle, DNA damage response, and regulation of apoptosis. | 0.754 |
| Dhx15 | RpII140 | FBpp0088040 | FBpp0310926 | DEAH-box helicase 15, isoform A; RNA helicase activity; RNA binding; ATP binding. It is involved in the biological process described with: positive regulation of p38MAPK cascade; mRNA splicing, via spliceosome. | DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] | 0.582 |
| Dhx15 | cass | FBpp0088040 | FBpp0080554 | DEAH-box helicase 15, isoform A; RNA helicase activity; RNA binding; ATP binding. It is involved in the biological process described with: positive regulation of p38MAPK cascade; mRNA splicing, via spliceosome. | Apoptosis inhibitor 5 homolog; Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis. | 0.540 |
| Dhx15 | pix | FBpp0088040 | FBpp0076284 | DEAH-box helicase 15, isoform A; RNA helicase activity; RNA binding; ATP binding. It is involved in the biological process described with: positive regulation of p38MAPK cascade; mRNA splicing, via spliceosome. | Pixie, isoform A; Pixie (pix) encodes ABCE1, which is an ATPase that functions as a translation recycling factor. It is required for the assembly of complexes involved in translation initiation, and plays a role in the regulation of cellular and organismal growth. | 0.799 |
| Dhx15 | scaf6 | FBpp0088040 | FBpp0075048 | DEAH-box helicase 15, isoform A; RNA helicase activity; RNA binding; ATP binding. It is involved in the biological process described with: positive regulation of p38MAPK cascade; mRNA splicing, via spliceosome. | SR-related CTD associated factor 6, isoform A; RNA binding. It is involved in the biological process described with: cellular calcium ion homeostasis; RNA processing. | 0.992 |
| RpII140 | Dhx15 | FBpp0310926 | FBpp0088040 | DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] | DEAH-box helicase 15, isoform A; RNA helicase activity; RNA binding; ATP binding. It is involved in the biological process described with: positive regulation of p38MAPK cascade; mRNA splicing, via spliceosome. | 0.582 |
| RpII140 | cass | FBpp0310926 | FBpp0080554 | DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] | Apoptosis inhibitor 5 homolog; Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis. | 0.999 |
| RpII140 | pix | FBpp0310926 | FBpp0076284 | DNA-directed RNA polymerase II subunit RPB2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB2 is [...] | Pixie, isoform A; Pixie (pix) encodes ABCE1, which is an ATPase that functions as a translation recycling factor. It is required for the assembly of complexes involved in translation initiation, and plays a role in the regulation of cellular and organismal growth. | 0.450 |
| bnl | cass | FBpp0083206 | FBpp0080554 | Branchless (bnl) encodes a Fibroblast Growth Factor (FGF) receptor for secreted FGF ligands that utilizes the intracellular Ras-MAP kinase pathway. It contributes to embryonic tracheal migration; Belongs to the heparin-binding growth factors family. | Apoptosis inhibitor 5 homolog; Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis. | 0.551 |
| cass | Aatf | FBpp0080554 | FBpp0078929 | Apoptosis inhibitor 5 homolog; Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis. | Protein Aatf; Apoptosis antagonizing transcription factor (Aatf) encodes a transcription factor that is a target of the kinases encoded by tefu and lok. It is involved in the control of the cell cycle, DNA damage response, and regulation of apoptosis. | 0.493 |
| cass | Acn | FBpp0080554 | FBpp0307803 | Apoptosis inhibitor 5 homolog; Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis. | Acinus, isoform A; Acinus (Acn) encodes nuclear protein that, together with the products of a Bin1 and RnpS1, forms the ASAP complex that contributes to the regulation of alternative splicing. The Acn protein also functions in basal, starvation-independent autophagy. | 0.552 |
| cass | BI-1 | FBpp0080554 | FBpp0076434 | Apoptosis inhibitor 5 homolog; Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis. | Bax inhibitor 1; Suppressor of apoptosis (By similarity). Modulates unfolded protein response signaling. Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation. | 0.521 |
| cass | CG5110 | FBpp0080554 | FBpp0297292 | Apoptosis inhibitor 5 homolog; Antiapoptotic factor. Also known to efficiently suppress E2F1-induced apoptosis. | Ragulator complex protein LAMTOR3 homolog; CG5110 encodes a scaffold protein that associates with the MAP kinase kinase and the MAP kinase encoded by Mekk1 and rl respectively. It regulates the vein promoting function of rl during wing imaginal disc development in third instar larvae; Belongs to the LAMTOR3 family. | 0.679 |