STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IFT46Intraflagellar transport 46; It is involved in the biological process described with: intraciliary transport; cilium assembly. (416 aa)    
Predicted Functional Partners:
IFT52
Intraflagellar transport 52.
   
 0.999
nompB
No mechanoreceptor potential B (nompB) encodes an essential component of the conserved intraflagellar transport mechanism, which is needed to extend cilia above the cell surface. nompB mutants have truncated, nonfunctional sensory cilia with consequent mechanosensory deficits.
   
 0.999
IFT57
Intraflagellar transport protein 57 homolog; Required for the formation of cilia; Belongs to the IFT57 family.
  
 0.998
Ttc26
Tetratricopeptide repeat domain 26; Intraciliary transport particle B binding. It is involved in the biological process described with: cilium assembly; intraciliary anterograde transport; intraciliary transport involved in cilium assembly.
  
 0.996
Oseg5
Outer segment 5; It is involved in the biological process described with: non-motile cilium assembly; cilium assembly.
  
 0.994
IFT54
Intraflagellar transport 54; Microtubule binding. It is involved in the biological process described with: regulation of microtubule cytoskeleton organization; intraciliary transport; cilium assembly.
   
 0.993
IFT20
Intraflagellar transport 20; It is involved in the biological process described with: centrosome localization; intraciliary transport; cilium assembly; protein localization to cilium.
    
 0.991
Oseg1
Outer segment 1 (Oseg1) encodes a protein required for ciliogenesis.
  
 
 0.984
Oseg6
Outer segment 6; It is involved in the biological process described with: intraciliary retrograde transport; cilium assembly; non-motile cilium assembly.
     
 0.970
Oseg2
Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. Belongs to the IFT172 family.
   
 0.968
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.