node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG6661 | CG9674 | FBpp0075512 | FBpp0297083 | GH20963p; 1-pyrroline-5-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: proline metabolic process; proline catabolic process to glutamate; oxidation-reduction process. | Uncharacterized protein, isoform F; It is involved in the biological process described with: glutamate biosynthetic process; ammonia assimilation cycle; oxidation-reduction process. | 0.916 |
CG6661 | Gdh | FBpp0075512 | FBpp0088988 | GH20963p; 1-pyrroline-5-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: proline metabolic process; proline catabolic process to glutamate; oxidation-reduction process. | Glutamate dehydrogenase, mitochondrial; Glutamate dehydrogenase (Gdh) encodes a glutamate dehydrogenase involved glutamate metabolism. | 0.919 |
CG6661 | Gs1 | FBpp0075512 | FBpp0077774 | GH20963p; 1-pyrroline-5-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: proline metabolic process; proline catabolic process to glutamate; oxidation-reduction process. | Glutamine synthetase 1 (Gs1) encodes the mitochondrial enzyme that uses glutamate and ammonia as substrates to synthesize glutamine, which is a precursor of purine and pyrimidine synthesis. An adequate level of maternally supplied Gs1 product activity is necessary in the early embryonic development. High level of glutamine in mitochondria causes megamitochondrial formation in cells. | 0.915 |
CG6661 | Gs2 | FBpp0075512 | FBpp0310162 | GH20963p; 1-pyrroline-5-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: proline metabolic process; proline catabolic process to glutamate; oxidation-reduction process. | Glutamine synthetase 2 (Gs2) encodes an enzyme that converts glutamate to glutamine. It is expressed in the embryonic nervous system and regulates the size of glutamate neurotransmitter pools and synapse assembly. | 0.915 |
CG6661 | L2HGDH | FBpp0075512 | FBpp0080728 | GH20963p; 1-pyrroline-5-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: proline metabolic process; proline catabolic process to glutamate; oxidation-reduction process. | L-2-hydroxyglutarate dehydrogenase, isoform A; (S)-2-hydroxy-acid oxidase activity; 2-hydroxyglutarate dehydrogenase activity. It is involved in the biological process described with: oxidation-reduction process. | 0.852 |
CG6661 | P5CDh1 | FBpp0075512 | FBpp0305036 | GH20963p; 1-pyrroline-5-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: proline metabolic process; proline catabolic process to glutamate; oxidation-reduction process. | delta-1-Pyrroline-5-carboxylate dehydrogenase 1 (P5CDh1) encodes a conserved, nuclear-encoded mitochondrial matrix enzyme. It is a member of the aldehyde dehydrogenase superfamily involved in proline degradation. | 0.906 |
CG6661 | bb8 | FBpp0075512 | FBpp0083774 | GH20963p; 1-pyrroline-5-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: proline metabolic process; proline catabolic process to glutamate; oxidation-reduction process. | Big bubble 8 (bb8) encodes a glutamate dehydrogenase involved in the development of the spermatid mitochondria; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.937 |
CG9674 | CG6661 | FBpp0297083 | FBpp0075512 | Uncharacterized protein, isoform F; It is involved in the biological process described with: glutamate biosynthetic process; ammonia assimilation cycle; oxidation-reduction process. | GH20963p; 1-pyrroline-5-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: proline metabolic process; proline catabolic process to glutamate; oxidation-reduction process. | 0.916 |
CG9674 | Gdh | FBpp0297083 | FBpp0088988 | Uncharacterized protein, isoform F; It is involved in the biological process described with: glutamate biosynthetic process; ammonia assimilation cycle; oxidation-reduction process. | Glutamate dehydrogenase, mitochondrial; Glutamate dehydrogenase (Gdh) encodes a glutamate dehydrogenase involved glutamate metabolism. | 0.993 |
CG9674 | Gs1 | FBpp0297083 | FBpp0077774 | Uncharacterized protein, isoform F; It is involved in the biological process described with: glutamate biosynthetic process; ammonia assimilation cycle; oxidation-reduction process. | Glutamine synthetase 1 (Gs1) encodes the mitochondrial enzyme that uses glutamate and ammonia as substrates to synthesize glutamine, which is a precursor of purine and pyrimidine synthesis. An adequate level of maternally supplied Gs1 product activity is necessary in the early embryonic development. High level of glutamine in mitochondria causes megamitochondrial formation in cells. | 0.964 |
CG9674 | Gs2 | FBpp0297083 | FBpp0310162 | Uncharacterized protein, isoform F; It is involved in the biological process described with: glutamate biosynthetic process; ammonia assimilation cycle; oxidation-reduction process. | Glutamine synthetase 2 (Gs2) encodes an enzyme that converts glutamate to glutamine. It is expressed in the embryonic nervous system and regulates the size of glutamate neurotransmitter pools and synapse assembly. | 0.966 |
CG9674 | L2HGDH | FBpp0297083 | FBpp0080728 | Uncharacterized protein, isoform F; It is involved in the biological process described with: glutamate biosynthetic process; ammonia assimilation cycle; oxidation-reduction process. | L-2-hydroxyglutarate dehydrogenase, isoform A; (S)-2-hydroxy-acid oxidase activity; 2-hydroxyglutarate dehydrogenase activity. It is involved in the biological process described with: oxidation-reduction process. | 0.857 |
CG9674 | Mdh1 | FBpp0297083 | FBpp0311560 | Uncharacterized protein, isoform F; It is involved in the biological process described with: glutamate biosynthetic process; ammonia assimilation cycle; oxidation-reduction process. | Malate dehydrogenase 1 (Mdh1) encodes a L-malate dehydrogenase involved in the interconversion of malate and oxaloacetate. | 0.829 |
CG9674 | Mdh2 | FBpp0297083 | FBpp0082985 | Uncharacterized protein, isoform F; It is involved in the biological process described with: glutamate biosynthetic process; ammonia assimilation cycle; oxidation-reduction process. | Malate dehydrogenase 2 (Mdh2) encodes one of the enzymes in the tricarboxylic acid cycle in mitochondria; Belongs to the LDH/MDH superfamily. | 0.832 |
CG9674 | P5CDh1 | FBpp0297083 | FBpp0305036 | Uncharacterized protein, isoform F; It is involved in the biological process described with: glutamate biosynthetic process; ammonia assimilation cycle; oxidation-reduction process. | delta-1-Pyrroline-5-carboxylate dehydrogenase 1 (P5CDh1) encodes a conserved, nuclear-encoded mitochondrial matrix enzyme. It is a member of the aldehyde dehydrogenase superfamily involved in proline degradation. | 0.918 |
CG9674 | bb8 | FBpp0297083 | FBpp0083774 | Uncharacterized protein, isoform F; It is involved in the biological process described with: glutamate biosynthetic process; ammonia assimilation cycle; oxidation-reduction process. | Big bubble 8 (bb8) encodes a glutamate dehydrogenase involved in the development of the spermatid mitochondria; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.993 |
D2hgdh | Gs1 | FBpp0070367 | FBpp0077774 | D-2-hydroxyglutaric acid dehydrogenase (D2hgdh) encodes an enzyme involved in oxidation-reduction metabolism. | Glutamine synthetase 1 (Gs1) encodes the mitochondrial enzyme that uses glutamate and ammonia as substrates to synthesize glutamine, which is a precursor of purine and pyrimidine synthesis. An adequate level of maternally supplied Gs1 product activity is necessary in the early embryonic development. High level of glutamine in mitochondria causes megamitochondrial formation in cells. | 0.402 |
D2hgdh | Gs2 | FBpp0070367 | FBpp0310162 | D-2-hydroxyglutaric acid dehydrogenase (D2hgdh) encodes an enzyme involved in oxidation-reduction metabolism. | Glutamine synthetase 2 (Gs2) encodes an enzyme that converts glutamate to glutamine. It is expressed in the embryonic nervous system and regulates the size of glutamate neurotransmitter pools and synapse assembly. | 0.401 |
D2hgdh | L2HGDH | FBpp0070367 | FBpp0080728 | D-2-hydroxyglutaric acid dehydrogenase (D2hgdh) encodes an enzyme involved in oxidation-reduction metabolism. | L-2-hydroxyglutarate dehydrogenase, isoform A; (S)-2-hydroxy-acid oxidase activity; 2-hydroxyglutarate dehydrogenase activity. It is involved in the biological process described with: oxidation-reduction process. | 0.873 |
Gdh | CG6661 | FBpp0088988 | FBpp0075512 | Glutamate dehydrogenase, mitochondrial; Glutamate dehydrogenase (Gdh) encodes a glutamate dehydrogenase involved glutamate metabolism. | GH20963p; 1-pyrroline-5-carboxylate dehydrogenase activity; oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: proline metabolic process; proline catabolic process to glutamate; oxidation-reduction process. | 0.919 |