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La protein (fruit fly) - STRING interaction network
La protein homolog in Drosophila melanogaster
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
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LaLa protein homolog; May be involved in transcription termination by RNA polymerase III. Binds RNA and DNA. Binds to precursors of RNA polymerase III transcripts. May play a specialized role during fly development (390 aa)    
Predicted Functional Partners:
CG6937
CG6937; mRNA binding; nucleotide binding; nucleic acid binding. It is involved in the biological process described with- neurogenesis (356 aa)
     
 
  0.966
Nop60B
H/ACA ribonucleoprotein complex subunit 4; Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine (’psi’) residues may serve to stabilize the conformation of rRNAs. Required for maintenance of the germline stem cell lineage during spermatogenesis; Belongs to the pseudouridine synthase TruB family (508 aa)
     
      0.950
vig2
Vig2, isoform B; It is involved in the biological process described with- regulation of chromatin silencing; histone H3-K9 methylation; heterochromatin organization (443 aa)
     
   
  0.949
nop5
CG10206-PA; It is involved in the biological process described with- rRNA processing (511 aa)
     
      0.947
hoip
NHP2-like protein 1 homolog; Binds to the 5’-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding (By similarity) (127 aa)
     
      0.938
NHP2
H/ACA ribonucleoprotein complex subunit 2-like protein; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs (By similarity) (160 aa)
     
      0.916
Nop56
Nucleolar KKE/D repeat protein; It is involved in the biological process described with- neurogenesis (496 aa)
     
      0.914
Fib
rRNA 2’-O-methyltransferase fibrillarin; S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L- methionine to catalyze the site-specific 2’-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of ’G [...] (344 aa)
     
 
  0.912
CG32409
Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly (349 aa)
     
        0.903
P32
CG6459 protein; P32 is an evolutionarily conserved mitochondrial protein. P32 functions in presynaptic calcium signaling and neurotransmitter release as well as chromatin metabolism (263 aa)
     
   
  0.901
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Drosophila melanogaster, fruit fly
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