STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG17570Uncharacterized protein. (134 aa)    
Predicted Functional Partners:
Cyp316a1
Probable cytochrome P450 316a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
      
 0.669
RNaseX25
Endoribonuclease activity; RNA binding; ribonuclease T2 activity; ribonuclease activity. It is involved in the biological process described with: RNA catabolic process; multicellular organism reproduction; Belongs to the RNase T2 family.
      
 0.652
AANATL3
Arylalkylamine N-acetyltransferase-like 3; N-acetyltransferase activity.
   
  
 0.629
CG31674
FI03731p; Glyoxylate reductase (NADP) activity; NAD binding; glycerate dehydrogenase activity; hydroxypyruvate reductase activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. It is involved in the biological process described with: oxidation-reduction process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
      
 0.606
Cyp4d8
Cytochrome P450 4d8; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
      
 0.601
CG8562
FI02848p; Metallocarboxypeptidase activity; zinc ion binding. It is involved in the biological process described with: proteolysis.
   
  
 0.567
Urm1
Ubiquitin-related modifier 1 homolog; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln) (By similarity). Serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3 (By similarity). The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U (By similarity). Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as Jafrac1, Ciao1, Eip71CD and GIL [...]
      
 0.548
pst
Pastrel, isoform F; Pastrel (pst) encodes a protein involved in long-term memory and protein secretion.
      
 0.491
Taf13
TBP-associated factor 13; DNA binding; protein heterodimerization activity; RNA polymerase II general transcription initiation factor activity; transcription coregulator activity. It is involved in the biological process described with: transcription initiation from RNA polymerase II promoter; regulation of transcription by RNA polymerase II.
      
 0.465
Mdr65
Multidrug resistance protein homolog 65; Multi drug resistance 65 (Mdr65) encodes a member of the MRP/ABCC subfamily of ATP-binding cassette (ABC) transporters. It is involved in humoral/CNS barrier drug exclusion and response to insecticide; Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
      
 0.430
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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