STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brunProtein brunelleschi; Cooperates with Rab11 and fwd/PI4K to mediate the flow of membrane through the Golgi, which is required to support cleavage furrow ingression, therefore promoting cytokinesis in male meiotic cells. (1320 aa)    
Predicted Functional Partners:
Trs20
Probable trafficking protein particle complex subunit 2; May play a role in vesicular transport from endoplasmic reticulum to Golgi. Involved in dsRNA uptake.
    
 0.998
SIDL
Trafficking protein particle complex subunit 10; May play a role in vesicular transport from endoplasmic reticulum to Golgi (By similarity). Has a role in one of the several mechanisms underlying dendritic localization of Shal channels.
   
 0.998
Trs31
Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi.
    
 0.998
Bet3
Trafficking protein particle complex subunit; Blocked early in transport 3 (Bet3) encodes a protein involved in dsRNA transport; Belongs to the TRAPP small subunits family. BET3 subfamily.
   
 0.998
Trs23
Trafficking protein particle complex subunit; Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: endoplasmic reticulum to Golgi vesicle-mediated transport; vesicle-mediated transport; Golgi vesicle transport; Belongs to the TRAPP small subunits family.
   
 0.997
Bet5
Trafficking protein particle complex subunit; Rab guanyl-nucleotide exchange factor activity. It is involved in the biological process described with: Golgi vesicle transport; vesicle-mediated transport; endoplasmic reticulum to Golgi vesicle-mediated transport; Belongs to the TRAPP small subunits family.
    
 0.997
CG9067
Uncharacterized protein; It is involved in the biological process described with: Golgi vesicle transport; endoplasmic reticulum to Golgi vesicle-mediated transport.
    
 0.997
Trs33
TRAPP subunit 33; It is involved in the biological process described with: regulation of GTPase activity; vesicle-mediated transport; Golgi vesicle transport; endoplasmic reticulum to Golgi vesicle-mediated transport.
   
 0.994
CG11396
RE19263p; Endopeptidase activity. It is involved in the biological process described with: Golgi vesicle transport.
   
 0.982
gry
Gryzun (gry) encodes a protein required for secretion that localizes to the early Golgi apparatus. It has been implicated in memory formation.
   
 
 0.981
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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