STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG9328FI14214p; It is involved in the biological process described with: regulation of cell growth. (180 aa)    
Predicted Functional Partners:
CG11619
Uncharacterized protein; Glycerophosphocholine phosphodiesterase activity; starch binding. It is involved in the biological process described with: glycerophospholipid catabolic process.
    
 
 0.840
qless
Qless, isoform A; Qless (qless) encodes a protein involved in the synthesis of the isoprenoid side chain of Coenzyme Q, a lipid component of the mitochondrial electron transport chain; Belongs to the FPP/GGPP synthase family.
    
 
 0.793
nito
RNA-binding protein spenito; RNA-binding protein that acts as an associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of mRNAs. M6a modification plays a role in the efficiency of mRNA splicing and is required for sex determination. In the WMM complex, may act by binding target RNAs and recruiting the WMM complex. Required for sex determination and dosage compensation via Sxl alternative splicing: m6A methylation acts as a key regulator of Sxl pre-mRNA and promotes female-specific alternative splicing of Sxl, which determines female physi [...]
   
 
 0.673
IP3K1
Kinase; Inositol 1,4,5-triphosphate kinase 1 (IP3K1) encodes a protein involved in response to oxidative stress; Belongs to the inositol phosphokinase (IPK) family.
      
 0.672
hoe1
Hoepel1, isoform C; It is involved in the biological process described with: transmembrane transport.
      
 0.609
Cip4
Cdc42-interacting protein 4 (Cip4) encodes an F-BAR protein that functions as an adaptor protein regulating membrane curvature and dynamics.
   
 
 0.520
mt:ND3
NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
    
 
 0.511
mt:ND1
NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
    
   0.501
ND-23
NADH dehydrogenase (Ubiquinone) 23 kDa subunit; NADH dehydrogenase activity; 4 iron, 4 sulfur cluster binding. It is involved in the biological process described with: aerobic respiration; mitochondrial ATP synthesis coupled electron transport; mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly.
    
   0.489
mt:ND4L
NADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
    
   0.489
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.