twit protein (fruit fly) - STRING interaction network

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twit

Target of wit (twit) encodes a GPI-anchored membrane ligand of the Ly6 family that participates in retrograde signalling as a downstream target of the BMP pathway receptor encoded by wit. It acts in neurons, regulating spontaneous neurotransmitter release during the maturation of larval neuromuscular junctions. (166 aa)

Predicted Functional Partners:

CG31675

0.820

CG14401

0.817

CG7781

0.689

CG9338

0.680

CG6583

0.654

CG14274

0.590

CG1607

0.533

crok

0.519

glec

0.515

CG10962

0.514

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CG10962	CG1607	FBpp0071206	FBpp0306617	FI06485p; 17-beta-ketosteroid reductase activity; estradiol 17-beta-dehydrogenase activity; 3-keto sterol reductase activity; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein, isoform C; L-amino acid transmembrane transporter activity; amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport.	0.522
CG10962	twit	FBpp0071206	FBpp0080955	FI06485p; 17-beta-ketosteroid reductase activity; estradiol 17-beta-dehydrogenase activity; 3-keto sterol reductase activity; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Target of wit (twit) encodes a GPI-anchored membrane ligand of the Ly6 family that participates in retrograde signalling as a downstream target of the BMP pathway receptor encoded by wit. It acts in neurons, regulating spontaneous neurotransmitter release during the maturation of larval neuromuscular junctions.	0.514
CG14274	CG7781	FBpp0079224	FBpp0312112	IP04187p.	GEO08076p1.	0.897
CG14274	twit	FBpp0079224	FBpp0080955	IP04187p.	Target of wit (twit) encodes a GPI-anchored membrane ligand of the Ly6 family that participates in retrograde signalling as a downstream target of the BMP pathway receptor encoded by wit. It acts in neurons, regulating spontaneous neurotransmitter release during the maturation of larval neuromuscular junctions.	0.590
CG14401	CG31675	FBpp0297992	FBpp0080958	Uncharacterized protein, isoform B.	RE19849p.	0.915
CG14401	CG6583	FBpp0297992	FBpp0079940	Uncharacterized protein, isoform B.	GEO13220p1.	0.910
CG14401	twit	FBpp0297992	FBpp0080955	Uncharacterized protein, isoform B.	Target of wit (twit) encodes a GPI-anchored membrane ligand of the Ly6 family that participates in retrograde signalling as a downstream target of the BMP pathway receptor encoded by wit. It acts in neurons, regulating spontaneous neurotransmitter release during the maturation of larval neuromuscular junctions.	0.817
CG1607	CG10962	FBpp0306617	FBpp0071206	Uncharacterized protein, isoform C; L-amino acid transmembrane transporter activity; amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport.	FI06485p; 17-beta-ketosteroid reductase activity; estradiol 17-beta-dehydrogenase activity; 3-keto sterol reductase activity; 17-beta-hydroxysteroid dehydrogenase (NADP+) activity; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	0.522
CG1607	twit	FBpp0306617	FBpp0080955	Uncharacterized protein, isoform C; L-amino acid transmembrane transporter activity; amino acid transmembrane transporter activity. It is involved in the biological process described with: amino acid transmembrane transport.	Target of wit (twit) encodes a GPI-anchored membrane ligand of the Ly6 family that participates in retrograde signalling as a downstream target of the BMP pathway receptor encoded by wit. It acts in neurons, regulating spontaneous neurotransmitter release during the maturation of larval neuromuscular junctions.	0.533
CG31675	CG14401	FBpp0080958	FBpp0297992	RE19849p.	Uncharacterized protein, isoform B.	0.915
CG31675	CG6583	FBpp0080958	FBpp0079940	RE19849p.	GEO13220p1.	0.910
CG31675	crok	FBpp0080958	FBpp0079924	RE19849p.	GEO12654p1; GPI anchor binding. It is involved in the biological process described with: septate junction assembly; sleep; positive regulation of voltage-gated potassium channel activity; regulation of tube size, open tracheal system; regulation of synaptic transmission, cholinergic.	0.814
CG31675	twit	FBpp0080958	FBpp0080955	RE19849p.	Target of wit (twit) encodes a GPI-anchored membrane ligand of the Ly6 family that participates in retrograde signalling as a downstream target of the BMP pathway receptor encoded by wit. It acts in neurons, regulating spontaneous neurotransmitter release during the maturation of larval neuromuscular junctions.	0.820
CG6583	CG14401	FBpp0079940	FBpp0297992	GEO13220p1.	Uncharacterized protein, isoform B.	0.910
CG6583	CG31675	FBpp0079940	FBpp0080958	GEO13220p1.	RE19849p.	0.910
CG6583	CG9338	FBpp0079940	FBpp0305224	GEO13220p1.	GEO04151p1.	0.829
CG6583	crok	FBpp0079940	FBpp0079924	GEO13220p1.	GEO12654p1; GPI anchor binding. It is involved in the biological process described with: septate junction assembly; sleep; positive regulation of voltage-gated potassium channel activity; regulation of tube size, open tracheal system; regulation of synaptic transmission, cholinergic.	0.967
CG6583	twit	FBpp0079940	FBpp0080955	GEO13220p1.	Target of wit (twit) encodes a GPI-anchored membrane ligand of the Ly6 family that participates in retrograde signalling as a downstream target of the BMP pathway receptor encoded by wit. It acts in neurons, regulating spontaneous neurotransmitter release during the maturation of larval neuromuscular junctions.	0.654
CG7781	CG14274	FBpp0312112	FBpp0079224	GEO08076p1.	IP04187p.	0.897
CG7781	twit	FBpp0312112	FBpp0080955	GEO08076p1.	Target of wit (twit) encodes a GPI-anchored membrane ligand of the Ly6 family that participates in retrograde signalling as a downstream target of the BMP pathway receptor encoded by wit. It acts in neurons, regulating spontaneous neurotransmitter release during the maturation of larval neuromuscular junctions.	0.689

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