STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG31675RE19849p. (148 aa)    
Predicted Functional Partners:
CG14401
Uncharacterized protein, isoform B.
      
 0.915
CG6583
GEO13220p1.
      
 0.909
CG31676
GEO08323p1.
   
  
 0.839
twit
Target of wit (twit) encodes a GPI-anchored membrane ligand of the Ly6 family that participates in retrograde signalling as a downstream target of the BMP pathway receptor encoded by wit. It acts in neurons, regulating spontaneous neurotransmitter release during the maturation of larval neuromuscular junctions.
   
  
 0.835
crok
GEO12654p1; GPI anchor binding. It is involved in the biological process described with: septate junction assembly; sleep; positive regulation of voltage-gated potassium channel activity; regulation of tube size, open tracheal system; regulation of synaptic transmission, cholinergic.
      
 0.796
atilla
Atilla, isoform B.
   
  
 0.673
inv
Homeobox protein invected; Engrailed (en) and invected (inv) are functionally redundant transcription factors in neuronal precursor cell NB5-3 specification. Inv is unable to substitute for en in other regulatory processes such as maintaining gsb expression in the neuroectoderm after stage 10 of embryogenesis. Maintenance of gsb expression in row 5 of the neuroectoderm involves an as yet unidentified short range signaling molecule.
      
 0.440
CG5597
GH04238p.
   
    0.426
CG8519
RE30129p; GTP binding; GTPase activity. It is involved in the biological process described with: signal transduction.
   
    0.412
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.