| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Apoltp | Hmgcr | FBpp0292877 | FBpp0083842 | Apolipoprotein lipid transfer particle (Apoltp) encodes a apolipoprotein of the ApoB family. It is assembled with lipids to form high density, low abundance lipoproteins named lipid transfer particles (LTP). LTP catalyzes the transfer of lipids from the gut to circulating lipophorin and from lipophorin to peripheral tissues, such as imaginal discs and ovaries. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Synthesis of mevalonate for the production of non-sterol isoprenoids, which are essential for growth differentiation. Provides spatial information during embryogenesis to guide migrating primordial germ cells (the pole cells) from the ectoderm to the mesoderm. Also required for association of the pole cells with the gonadal mesoderm. Belongs to the HMG-CoA reductase family. | 0.468 |
| Apoltp | Mtp | FBpp0292877 | FBpp0080968 | Apolipoprotein lipid transfer particle (Apoltp) encodes a apolipoprotein of the ApoB family. It is assembled with lipids to form high density, low abundance lipoproteins named lipid transfer particles (LTP). LTP catalyzes the transfer of lipids from the gut to circulating lipophorin and from lipophorin to peripheral tissues, such as imaginal discs and ovaries. | Microsomal triacylglycerol transfer protein (Mtp) encodes a phosphatidylcholine transporter involved in lipoprotein metabolism, tracheal system lumen formation and neuron development. | 0.966 |
| Apoltp | apolpp | FBpp0292877 | FBpp0306689 | Apolipoprotein lipid transfer particle (Apoltp) encodes a apolipoprotein of the ApoB family. It is assembled with lipids to form high density, low abundance lipoproteins named lipid transfer particles (LTP). LTP catalyzes the transfer of lipids from the gut to circulating lipophorin and from lipophorin to peripheral tissues, such as imaginal discs and ovaries. | Apolipophorin-1; Constitutes the major component of lipophorin, which mediates transport for various types of lipids in hemolymph. Acts by forming lipoprotein particles that bind lipoproteins and lipids. Also involved in the transport of hydrophobic ligands like juvenile hormones, pheromone hydrocarbons and carotenoids. Required for morphogens wingless (wg) and hedgehog (hh) function, probably by acting as vehicles for the movement of wg and hh, explaining how covalently lipidated wg and hh can spread over long distances. May also be involved in transport and/or metabolism of heme. | 0.511 |
| Apoltp | cv-d | FBpp0292877 | FBpp0082643 | Apolipoprotein lipid transfer particle (Apoltp) encodes a apolipoprotein of the ApoB family. It is assembled with lipids to form high density, low abundance lipoproteins named lipid transfer particles (LTP). LTP catalyzes the transfer of lipids from the gut to circulating lipophorin and from lipophorin to peripheral tissues, such as imaginal discs and ovaries. | Crossveinless d (cv-d) encodes the sole Drosophila member of an insect vitellogenin-like lipoprotein family. It can bind lipids and members of the BMP protein family. Loss of cv-d produces viable flies with disrupted BMP signaling in the developing wing. | 0.527 |
| CAHbeta | Mtp | FBpp0081438 | FBpp0080968 | Carbonic anhydrase beta (CAHbeta) encodes a beta-class carbonate dehydratase that catalyzes the reversible hydration/dehydration of carbon dioxide to bicarbonate and protons. | Microsomal triacylglycerol transfer protein (Mtp) encodes a phosphatidylcholine transporter involved in lipoprotein metabolism, tracheal system lumen formation and neuron development. | 0.647 |
| CG10932 | Hmgcr | FBpp0311869 | FBpp0083842 | LD24105p; acetyl-CoA C-acetyltransferase activity; acetyl-CoA C-acyltransferase activity. It is involved in the biological process described with: fatty acid beta-oxidation; fatty acid biosynthetic process; pyruvate metabolic process; Belongs to the thiolase-like superfamily. Thiolase family. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Synthesis of mevalonate for the production of non-sterol isoprenoids, which are essential for growth differentiation. Provides spatial information during embryogenesis to guide migrating primordial germ cells (the pole cells) from the ectoderm to the mesoderm. Also required for association of the pole cells with the gonadal mesoderm. Belongs to the HMG-CoA reductase family. | 0.647 |
| CG10932 | Mtp | FBpp0311869 | FBpp0080968 | LD24105p; acetyl-CoA C-acetyltransferase activity; acetyl-CoA C-acyltransferase activity. It is involved in the biological process described with: fatty acid beta-oxidation; fatty acid biosynthetic process; pyruvate metabolic process; Belongs to the thiolase-like superfamily. Thiolase family. | Microsomal triacylglycerol transfer protein (Mtp) encodes a phosphatidylcholine transporter involved in lipoprotein metabolism, tracheal system lumen formation and neuron development. | 0.621 |
| CG10932 | adp | FBpp0311869 | FBpp0085923 | LD24105p; acetyl-CoA C-acetyltransferase activity; acetyl-CoA C-acyltransferase activity. It is involved in the biological process described with: fatty acid beta-oxidation; fatty acid biosynthetic process; pyruvate metabolic process; Belongs to the thiolase-like superfamily. Thiolase family. | Adipose, isoform A; Adipose (adp) encodes a protein involved in lipid metabolism and fat storage. | 0.598 |
| Hmgcr | Apoltp | FBpp0083842 | FBpp0292877 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Synthesis of mevalonate for the production of non-sterol isoprenoids, which are essential for growth differentiation. Provides spatial information during embryogenesis to guide migrating primordial germ cells (the pole cells) from the ectoderm to the mesoderm. Also required for association of the pole cells with the gonadal mesoderm. Belongs to the HMG-CoA reductase family. | Apolipoprotein lipid transfer particle (Apoltp) encodes a apolipoprotein of the ApoB family. It is assembled with lipids to form high density, low abundance lipoproteins named lipid transfer particles (LTP). LTP catalyzes the transfer of lipids from the gut to circulating lipophorin and from lipophorin to peripheral tissues, such as imaginal discs and ovaries. | 0.468 |
| Hmgcr | CG10932 | FBpp0083842 | FBpp0311869 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Synthesis of mevalonate for the production of non-sterol isoprenoids, which are essential for growth differentiation. Provides spatial information during embryogenesis to guide migrating primordial germ cells (the pole cells) from the ectoderm to the mesoderm. Also required for association of the pole cells with the gonadal mesoderm. Belongs to the HMG-CoA reductase family. | LD24105p; acetyl-CoA C-acetyltransferase activity; acetyl-CoA C-acyltransferase activity. It is involved in the biological process described with: fatty acid beta-oxidation; fatty acid biosynthetic process; pyruvate metabolic process; Belongs to the thiolase-like superfamily. Thiolase family. | 0.647 |
| Hmgcr | Mtp | FBpp0083842 | FBpp0080968 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Synthesis of mevalonate for the production of non-sterol isoprenoids, which are essential for growth differentiation. Provides spatial information during embryogenesis to guide migrating primordial germ cells (the pole cells) from the ectoderm to the mesoderm. Also required for association of the pole cells with the gonadal mesoderm. Belongs to the HMG-CoA reductase family. | Microsomal triacylglycerol transfer protein (Mtp) encodes a phosphatidylcholine transporter involved in lipoprotein metabolism, tracheal system lumen formation and neuron development. | 0.749 |
| Hmgcr | SREBP | FBpp0083842 | FBpp0074643 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Synthesis of mevalonate for the production of non-sterol isoprenoids, which are essential for growth differentiation. Provides spatial information during embryogenesis to guide migrating primordial germ cells (the pole cells) from the ectoderm to the mesoderm. Also required for association of the pole cells with the gonadal mesoderm. Belongs to the HMG-CoA reductase family. | Sterol regulatory element binding protein (SREBP) encodes a membrane protein that functions as a master-regulator of lipogenesis. It activates transcription of lipogenic genes upon reduction of lipid or cholesterol levels. | 0.977 |
| Hmgcr | apolpp | FBpp0083842 | FBpp0306689 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Synthesis of mevalonate for the production of non-sterol isoprenoids, which are essential for growth differentiation. Provides spatial information during embryogenesis to guide migrating primordial germ cells (the pole cells) from the ectoderm to the mesoderm. Also required for association of the pole cells with the gonadal mesoderm. Belongs to the HMG-CoA reductase family. | Apolipophorin-1; Constitutes the major component of lipophorin, which mediates transport for various types of lipids in hemolymph. Acts by forming lipoprotein particles that bind lipoproteins and lipids. Also involved in the transport of hydrophobic ligands like juvenile hormones, pheromone hydrocarbons and carotenoids. Required for morphogens wingless (wg) and hedgehog (hh) function, probably by acting as vehicles for the movement of wg and hh, explaining how covalently lipidated wg and hh can spread over long distances. May also be involved in transport and/or metabolism of heme. | 0.468 |
| Mtp | Apoltp | FBpp0080968 | FBpp0292877 | Microsomal triacylglycerol transfer protein (Mtp) encodes a phosphatidylcholine transporter involved in lipoprotein metabolism, tracheal system lumen formation and neuron development. | Apolipoprotein lipid transfer particle (Apoltp) encodes a apolipoprotein of the ApoB family. It is assembled with lipids to form high density, low abundance lipoproteins named lipid transfer particles (LTP). LTP catalyzes the transfer of lipids from the gut to circulating lipophorin and from lipophorin to peripheral tissues, such as imaginal discs and ovaries. | 0.966 |
| Mtp | CAHbeta | FBpp0080968 | FBpp0081438 | Microsomal triacylglycerol transfer protein (Mtp) encodes a phosphatidylcholine transporter involved in lipoprotein metabolism, tracheal system lumen formation and neuron development. | Carbonic anhydrase beta (CAHbeta) encodes a beta-class carbonate dehydratase that catalyzes the reversible hydration/dehydration of carbon dioxide to bicarbonate and protons. | 0.647 |
| Mtp | CG10932 | FBpp0080968 | FBpp0311869 | Microsomal triacylglycerol transfer protein (Mtp) encodes a phosphatidylcholine transporter involved in lipoprotein metabolism, tracheal system lumen formation and neuron development. | LD24105p; acetyl-CoA C-acetyltransferase activity; acetyl-CoA C-acyltransferase activity. It is involved in the biological process described with: fatty acid beta-oxidation; fatty acid biosynthetic process; pyruvate metabolic process; Belongs to the thiolase-like superfamily. Thiolase family. | 0.621 |
| Mtp | Hmgcr | FBpp0080968 | FBpp0083842 | Microsomal triacylglycerol transfer protein (Mtp) encodes a phosphatidylcholine transporter involved in lipoprotein metabolism, tracheal system lumen formation and neuron development. | 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Synthesis of mevalonate for the production of non-sterol isoprenoids, which are essential for growth differentiation. Provides spatial information during embryogenesis to guide migrating primordial germ cells (the pole cells) from the ectoderm to the mesoderm. Also required for association of the pole cells with the gonadal mesoderm. Belongs to the HMG-CoA reductase family. | 0.749 |
| Mtp | Pdi | FBpp0080968 | FBpp0312224 | Microsomal triacylglycerol transfer protein (Mtp) encodes a phosphatidylcholine transporter involved in lipoprotein metabolism, tracheal system lumen formation and neuron development. | Protein disulfide-isomerase; Participates in the folding of proteins containing disulfide bonds. | 0.941 |
| Mtp | Pdp | FBpp0080968 | FBpp0298274 | Microsomal triacylglycerol transfer protein (Mtp) encodes a phosphatidylcholine transporter involved in lipoprotein metabolism, tracheal system lumen formation and neuron development. | Pyruvate dehydrogenase phosphatase (Pdp) encodes an enzyme that regulates the BMP/DPP pathway via dephosporylation of the product encoded by Mad. | 0.647 |
| Mtp | SREBP | FBpp0080968 | FBpp0074643 | Microsomal triacylglycerol transfer protein (Mtp) encodes a phosphatidylcholine transporter involved in lipoprotein metabolism, tracheal system lumen formation and neuron development. | Sterol regulatory element binding protein (SREBP) encodes a membrane protein that functions as a master-regulator of lipogenesis. It activates transcription of lipogenic genes upon reduction of lipid or cholesterol levels. | 0.708 |
