STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Edg84APupal cuticle protein Edg-84A; Ecdysone-dependent gene 84A (Edg84A) encodes a pupal cuticle protein, assumed to be component of the exocuticle. Edg84A is expressed only in anterior epidermis during the late prepupal period, induced by the transcription factor encoded by ftz-f1. (188 aa)    
Predicted Functional Partners:
Edg78E
Pupal cuticle protein Edg-78E; Ecdysone-dependent gene 78E (Edg78E) encodes a pupal cuticle protein that is induced by ecdysone during prepupal development. It is only found in the pupal exocuticle where it binds chitin and serves as part of the structural basis of the cuticle.
   
 
 0.791
Lcp65Ad
Cuticle protein LCP65Ad; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development.
   
    0.635
Pcp
Pupal cuticle protein; Component of the cuticle of the pupa of fruit fly.
   
 
 0.606
Lcp65Ab1
Lcp65Ab1 (Lcp65Ab1) encodes a small structural protein of the chitin based larval cuticle.
      
 0.601
ftz-f1
Nuclear hormone receptor FTZ-F1; Acts as a cofactor to fushi tarazu (ftz). Facilitates the binding of ftz to DNA. Binds the sequence element 5'-YCYYGGYCR-3' in the zebra element of ftz. Probably also functions as a receptor for a yet unknown ligand; Belongs to the nuclear hormone receptor family. NR5 subfamily.
    
 
 0.552
Pgant6
N-acetylgalactosaminyltransferase 6; Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D- galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide s [...]
      
 0.497
Eig71Ec
Ecdysone-induced gene 71Ec; It is involved in the biological process described with: defense response to bacterium; metamorphosis.
   
  
 0.497
Lcp2
Larval cuticle protein 2; Component of the larval cuticle.
    
 
 0.497
Cyp6a13
Probable cytochrome P450 6a13; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
   
 
 0.495
Lcp65Ab2
Larval cuticle protein 65Ab1; Component of the cuticle of the larva.
      
 0.430
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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