node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Taf1 | Taf10 | FBpp0293442 | FBpp0077401 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | 0.997 |
Taf1 | Taf11 | FBpp0293442 | FBpp0079514 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | TBP-associated factor 11 (Taf11) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. It enhances RNA interference efficiency, organizing the assembly of the RISC loading complex. | 0.999 |
Taf1 | Taf12 | FBpp0293442 | FBpp0081918 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | TBP-associated factor 12 (Taf12) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it is important for its stability. It forms a histone-like pair with Taf4. Taf12 is also an integral component of the Drosophila SAGA histone acetyltransferase complex. | 0.999 |
Taf1 | Taf13 | FBpp0293442 | FBpp0080872 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | TBP-associated factor 13; DNA binding; protein heterodimerization activity; RNA polymerase II general transcription initiation factor activity; transcription coregulator activity. It is involved in the biological process described with: transcription initiation from RNA polymerase II promoter; regulation of transcription by RNA polymerase II. | 0.999 |
Taf1 | Taf2 | FBpp0293442 | FBpp0076090 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | TBP-associated factor 2 (Taf2) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. Together with the product of Taf1, it binds the Initiator and/or the DPE core promoter elements. | 0.999 |
Taf1 | Taf6 | FBpp0293442 | FBpp0074709 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | TBP-associated factor 6 (Taf6) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it might be important for its stability. It forms a histone-like pair with the product of e(y)1. It is required during all stages of development, but particularly during imaginal disc development and gametogenesis. | 0.999 |
Taf1 | Taf7 | FBpp0293442 | FBpp0081253 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | Transcription initiation factor TFIID subunit 7; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | 0.999 |
Taf1 | Taf8 | FBpp0293442 | FBpp0074288 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | Transcription initiation factor TFIID subunit 8; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | 0.996 |
Taf1 | Tbp | FBpp0293442 | FBpp0071596 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | TATA binding protein (Tbp) encodes a basal transcription factor required at most RNA Pol I and Pol II-transcribed genes. Traditionally thought to be recruited only to TATA box containing promoters, recent work shows that promoters with very weak TATA box consensus sequences also recruit the product of Tbp as a part of the multisubunit TFIID basal transcription factor or via the SAGA histone acetyltransferase complex. | 0.999 |
Taf1 | bip2 | FBpp0293442 | FBpp0088179 | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | Bip2 (bip2) encodes a protein that interacts with the transcription factor encoded by Trl and is involved in transcriptional activation. | 0.999 |
Taf10 | Taf1 | FBpp0077401 | FBpp0293442 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | Transcription initiation factor TFIID subunit 1; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Largest component and core scaffold of the complex. Contains N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Negative regulator of the TATA box-binding activity of Tbp. | 0.997 |
Taf10 | Taf11 | FBpp0077401 | FBpp0079514 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | TBP-associated factor 11 (Taf11) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. It enhances RNA interference efficiency, organizing the assembly of the RISC loading complex. | 0.997 |
Taf10 | Taf12 | FBpp0077401 | FBpp0081918 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | TBP-associated factor 12 (Taf12) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it is important for its stability. It forms a histone-like pair with Taf4. Taf12 is also an integral component of the Drosophila SAGA histone acetyltransferase complex. | 0.999 |
Taf10 | Taf13 | FBpp0077401 | FBpp0080872 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | TBP-associated factor 13; DNA binding; protein heterodimerization activity; RNA polymerase II general transcription initiation factor activity; transcription coregulator activity. It is involved in the biological process described with: transcription initiation from RNA polymerase II promoter; regulation of transcription by RNA polymerase II. | 0.997 |
Taf10 | Taf2 | FBpp0077401 | FBpp0076090 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | TBP-associated factor 2 (Taf2) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. Together with the product of Taf1, it binds the Initiator and/or the DPE core promoter elements. | 0.997 |
Taf10 | Taf6 | FBpp0077401 | FBpp0074709 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | TBP-associated factor 6 (Taf6) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it might be important for its stability. It forms a histone-like pair with the product of e(y)1. It is required during all stages of development, but particularly during imaginal disc development and gametogenesis. | 0.999 |
Taf10 | Taf7 | FBpp0077401 | FBpp0081253 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | Transcription initiation factor TFIID subunit 7; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | 0.996 |
Taf10 | Taf8 | FBpp0077401 | FBpp0074288 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | Transcription initiation factor TFIID subunit 8; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | 0.998 |
Taf10 | Tbp | FBpp0077401 | FBpp0071596 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | TATA binding protein (Tbp) encodes a basal transcription factor required at most RNA Pol I and Pol II-transcribed genes. Traditionally thought to be recruited only to TATA box containing promoters, recent work shows that promoters with very weak TATA box consensus sequences also recruit the product of Tbp as a part of the multisubunit TFIID basal transcription factor or via the SAGA histone acetyltransferase complex. | 0.997 |
Taf10 | bip2 | FBpp0077401 | FBpp0088179 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | Bip2 (bip2) encodes a protein that interacts with the transcription factor encoded by Trl and is involved in transcriptional activation. | 0.999 |