STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG2678Uncharacterized zinc finger protein CG2678; May be involved in transcriptional regulation. (434 aa)    
Predicted Functional Partners:
CG3457
LD17911p.
   
  
 0.918
CG31808
GEO02462p1.
      
 0.835
pyx
Transient receptor potential channel pyrexia; Receptor-activated non-selective cation channel involved in protection or tolerance from high temperature stress. Activated by temperatures above 40 degrees Celsius. More permeable to K(+) than to Na(+). May act in stress protection allow flies to survive in natural environments.
    
 
 0.648
Dis3l2
Dis3 like 3'-5' exoribonuclease 2 (Dis3l2) encodes a 3'-5'-exoribonuclease involved in catabolism of miRNA and tRNA; Belongs to the RNR ribonuclease family.
    
 
 0.526
CG6813
Uncharacterized protein, isoform C; RNA polymerase II regulatory region sequence-specific DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; zinc ion binding; DNA-binding transcription factor activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated.
  
     0.492
nom
Numerous disordered muscles, isoform A; Zinc ion binding; DNA-binding transcription factor activity; DNA binding. It is involved in the biological process described with: larval somatic muscle development; regulation of transcription, DNA-templated.
  
    0.491
CG17806
LD32088p; DNA-binding transcription factor activity; zinc ion binding; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of gene expression; regulation of transcription, DNA-templated.
  
    0.484
CG18764
FI01424p; DNA-binding transcription factor activity; zinc ion binding; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated.
  
    0.469
CG1529
Uncharacterized protein, isoform C; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; sequence-specific DNA binding; zinc ion binding; DNA-binding transcription factor activity, RNA polymerase II-specific. It is involved in the biological process described with: negative regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II.
  
    0.468
CG31441
LD25880p; Zinc ion binding; transcription regulatory region sequence-specific DNA binding.
  
    0.466
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.