STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eloFElongation of very long chain fatty acids protein F; Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids, to yield products up to 30 carbons in length. May also elongate diunsaturated fatty acids. Important for courtship behavior where it probably has a role in female pheromone biosynthesis. (257 aa)    
Predicted Functional Partners:
Fad2
Fad2 (Fad2) encodes a transmembrane fatty acid desaturase that utilizes mono-unsaturated long-chain fatty acids (LCFAs) to synthesize di-unsaturated LCFAs. It is involved in the synthesis of the female pheromones.
   
 
 0.985
Elo68alpha
Elongation of very long chain fatty acids protein; Elongase 68alpha (Elo68alpha) encodes a transmembrane fatty acid elongase, elongating Delta9 unsaturated LCFAs (C14 and C16) to Delta11 LCFAs (C16 and C18), that is involved in the synthesis of the male pheromone cis-vaccenyl acetate.
  
  
0.930
CG6432
GH15945p; Catalytic activity; short-chain fatty acid-CoA ligase activity. It is involved in the biological process described with: fatty acid biosynthetic process.
   
  
 0.853
Desat1
Desaturase 1 (Desat1) encodes a transmembrane fatty acid desaturase that utilizes myristate and stearate (C16:0 and C18:0) to synthesize myristoleic and oleic acids (C16:1 and C18:1). It is involved in the synthesis of unsaturated fatty acids.
    
 
 0.840
Desat2
Fatty acid desaturase 2; stearoyl-CoA 9-desaturase activity; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; unsaturated fatty acid biosynthetic process; Belongs to the fatty acid desaturase type 1 family.
    
 
 0.683
spidey
RH59310p; Spidey (spidey) encodes a member of the short chain dehydrogenase/reductase family. It regulates oenocyte growth and maturation, as well as the metabolism of ecdysteroids and cuticular hydrocarbons; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.634
Cyp4g1
Cytochrome P450-4g1 (Cyp4g1) encodes the terminal oxidative decarbonylase in cuticular hydrocarbon biosynthesis within oenocytes.
   
  
 0.617
FASN3
Fatty acid synthase 3; Oxidoreductase activity; phosphopantetheine binding; fatty acid synthase activity; hydrolase activity, acting on ester bonds. It is involved in the biological process described with: biosynthetic process.
   
  
 0.615
CG30008
Elongation of very long chain fatty acids protein; Fatty acid elongase activity.
  
 
0.599
CG10097
Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
      
 0.548
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.