STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG6723FI02016p; Symporter activity. It is involved in the biological process described with: transmembrane transport; sodium ion transport; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (587 aa)    
Predicted Functional Partners:
CG45676
Uncharacterized protein.
      
 0.669
slgA
Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate.
  
  
 0.636
CG9657
FI02094p; Symporter activity. It is involved in the biological process described with: transmembrane transport; sodium ion transport; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
0.607
P5CS
Delta-1-pyrroline-5-carboxylate synthase; Glutamate-5-semialdehyde dehydrogenase activity; glutamate 5-kinase activity; delta1-pyrroline-5-carboxylate synthetase activity. It is involved in the biological process described with: oxidation-reduction process; proline biosynthetic process; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
     
 0.572
Tsf1
Transferrin 1 (Tsf1) encodes an iron binding protein induced during the immune response. Iron sequestration is a classical host defense mechanism to combat bacterial infection.
      
 0.495
Idgf4
Chitinase-like protein Idgf4; Cooperates with insulin-like peptides to stimulate the proliferation, polarization and motility of imaginal disk cells. May act by stabilizing the binding of insulin-like peptides to its receptor through a simultaneous interaction with both molecules to form a multiprotein signaling complex; Belongs to the glycosyl hydrolase 18 family. IDGF subfamily.
      
 0.491
Aprt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.447
AcCoAS
Acetyl-coenzyme A synthetase; Activates acetate so that it can be used for lipid synthesis or for energy generation; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.412
CG6432
GH15945p; Catalytic activity; short-chain fatty acid-CoA ligase activity. It is involved in the biological process described with: fatty acid biosynthetic process.
  
  
 0.412
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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