node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Saf6 | Spt20 | FBpp0077705 | FBpp0075554 | SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities. | Spt20, isoform A; Transcription coregulator activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; histone acetylation. | 0.999 |
Saf6 | Taf10 | FBpp0077705 | FBpp0077401 | SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities. | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | 0.711 |
Saf6 | Taf10b | FBpp0077705 | FBpp0077415 | SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities. | Transcription initiation factor TFIID subunit 10b; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | 0.999 |
Saf6 | Taf12 | FBpp0077705 | FBpp0081918 | SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities. | TBP-associated factor 12 (Taf12) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it is important for its stability. It forms a histone-like pair with Taf4. Taf12 is also an integral component of the Drosophila SAGA histone acetyltransferase complex. | 0.999 |
Saf6 | Taf6 | FBpp0077705 | FBpp0074709 | SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities. | TBP-associated factor 6 (Taf6) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it might be important for its stability. It forms a histone-like pair with the product of e(y)1. It is required during all stages of development, but particularly during imaginal disc development and gametogenesis. | 0.860 |
Saf6 | Tbp | FBpp0077705 | FBpp0071596 | SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities. | TATA binding protein (Tbp) encodes a basal transcription factor required at most RNA Pol I and Pol II-transcribed genes. Traditionally thought to be recruited only to TATA box containing promoters, recent work shows that promoters with very weak TATA box consensus sequences also recruit the product of Tbp as a part of the multisubunit TFIID basal transcription factor or via the SAGA histone acetyltransferase complex. | 0.621 |
Saf6 | e(y)1 | FBpp0077705 | FBpp0074237 | SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities. | Transcription initiation factor TFIID subunit 9; Enhancer of yellow 1 (e(y)1) encodes a TAF9 protein and a main component of the Transcription factor II D (TFIID) complex. TFIID is involved in recruiting the transcription machinery to core promoters and organizing specific enhancer-promoter interactions. | 0.999 |
Spt20 | Saf6 | FBpp0075554 | FBpp0077705 | Spt20, isoform A; Transcription coregulator activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; histone acetylation. | SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities. | 0.999 |
Spt20 | Taf10 | FBpp0075554 | FBpp0077401 | Spt20, isoform A; Transcription coregulator activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; histone acetylation. | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | 0.978 |
Spt20 | Taf10b | FBpp0075554 | FBpp0077415 | Spt20, isoform A; Transcription coregulator activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; histone acetylation. | Transcription initiation factor TFIID subunit 10b; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | 0.997 |
Spt20 | Taf12 | FBpp0075554 | FBpp0081918 | Spt20, isoform A; Transcription coregulator activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; histone acetylation. | TBP-associated factor 12 (Taf12) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it is important for its stability. It forms a histone-like pair with Taf4. Taf12 is also an integral component of the Drosophila SAGA histone acetyltransferase complex. | 0.999 |
Spt20 | Taf6 | FBpp0075554 | FBpp0074709 | Spt20, isoform A; Transcription coregulator activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; histone acetylation. | TBP-associated factor 6 (Taf6) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it might be important for its stability. It forms a histone-like pair with the product of e(y)1. It is required during all stages of development, but particularly during imaginal disc development and gametogenesis. | 0.924 |
Spt20 | Tbp | FBpp0075554 | FBpp0071596 | Spt20, isoform A; Transcription coregulator activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; histone acetylation. | TATA binding protein (Tbp) encodes a basal transcription factor required at most RNA Pol I and Pol II-transcribed genes. Traditionally thought to be recruited only to TATA box containing promoters, recent work shows that promoters with very weak TATA box consensus sequences also recruit the product of Tbp as a part of the multisubunit TFIID basal transcription factor or via the SAGA histone acetyltransferase complex. | 0.787 |
Spt20 | e(y)1 | FBpp0075554 | FBpp0074237 | Spt20, isoform A; Transcription coregulator activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; histone acetylation. | Transcription initiation factor TFIID subunit 9; Enhancer of yellow 1 (e(y)1) encodes a TAF9 protein and a main component of the Transcription factor II D (TFIID) complex. TFIID is involved in recruiting the transcription machinery to core promoters and organizing specific enhancer-promoter interactions. | 0.998 |
Taf10 | Saf6 | FBpp0077401 | FBpp0077705 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | SAGA factor-like TAF6 (Saf6) encodes a component of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) chromatin modifying complex. This complex is responsible for acetylation of histones and deubiquitination of the product of His2B at active promoters. The product of Saf6 replaces the product of mia within SAGA when the product of mia is restricted to the TFIID transcription complex. Notably, the product of Saf6 is essential for SAGA's co-activator function but does not impact either of its enzymatic activities. | 0.711 |
Taf10 | Spt20 | FBpp0077401 | FBpp0075554 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | Spt20, isoform A; Transcription coregulator activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II; histone acetylation. | 0.978 |
Taf10 | Taf10b | FBpp0077401 | FBpp0077415 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | Transcription initiation factor TFIID subunit 10b; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | 0.955 |
Taf10 | Taf11 | FBpp0077401 | FBpp0079514 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | TBP-associated factor 11 (Taf11) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. It enhances RNA interference efficiency, organizing the assembly of the RISC loading complex. | 0.997 |
Taf10 | Taf12 | FBpp0077401 | FBpp0081918 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | TBP-associated factor 12 (Taf12) encodes a protein that forms part of the multisubunit basal transcription factor TFIID, and it is important for its stability. It forms a histone-like pair with Taf4. Taf12 is also an integral component of the Drosophila SAGA histone acetyltransferase complex. | 0.999 |
Taf10 | Taf2 | FBpp0077401 | FBpp0076090 | Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. | TBP-associated factor 2 (Taf2) encodes a protein that forms part of the multisubunit basal transcription factor TFIID. Together with the product of Taf1, it binds the Initiator and/or the DPE core promoter elements. | 0.997 |