| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG9876 | Timp | FBpp0071889 | FBpp0081722 | FI01017p; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. | Tissue inhibitor of metalloproteinase; Metalloproteinase inhibitor that acts on both matrix metalloproteinases Mmp1 and Mmp2 in vitro. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor (By similarity). Required for wing maturation which is the final step in morphogenesis of the adult fly. Involved in the negative regulation of developmental tissue invasion for imaginal disk eversion during metamorphosis by inhibiting Mmp-mediated basement membrane (BM) degradation. Required for oogenesis and for the long-term maintainance of [...] | 0.728 |
| CG9876 | mfas | FBpp0071889 | FBpp0081972 | FI01017p; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. | Midline fasciclin, isoform J; Midline fasciclin (mfas) encodes a protein involved in axonogenesis and regulation of hemocyte proliferation. | 0.760 |
| CG9876 | net | FBpp0071889 | FBpp0288762 | FI01017p; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. | Net, isoform B; Net (net) encodes a basic helix-loop-helix protein that probably acts as a transcriptional repressor. During wing vein formation it is expressed in all interveins territories and antagonises the activity of the product of Egfr. | 0.738 |
| CG9876 | scf | FBpp0071889 | FBpp0088881 | FI01017p; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. | Supercoiling factor (scf) encodes two polypeptides: DCB45 and its N-teminally truncated form Scf. Scf is a nuclear protein that introduces negative supercoils into DNA in conjunction with topoisomerase II. DCB45 is an endoplasmic reticulum-resident protein. | 0.767 |
| CG9876 | zetaCOP | FBpp0071889 | FBpp0075111 | FI01017p; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. | Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. | 0.602 |
| Cog6 | mfas | FBpp0087676 | FBpp0081972 | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Belongs to the COG6 family. | Midline fasciclin, isoform J; Midline fasciclin (mfas) encodes a protein involved in axonogenesis and regulation of hemocyte proliferation. | 0.511 |
| GC | mfas | FBpp0072701 | FBpp0081972 | Gamma-glutamyl carboxylase (GC) encodes an enzyme involved in peptidyl-glutamic acid carboxylation. | Midline fasciclin, isoform J; Midline fasciclin (mfas) encodes a protein involved in axonogenesis and regulation of hemocyte proliferation. | 0.562 |
| GC | scf | FBpp0072701 | FBpp0088881 | Gamma-glutamyl carboxylase (GC) encodes an enzyme involved in peptidyl-glutamic acid carboxylation. | Supercoiling factor (scf) encodes two polypeptides: DCB45 and its N-teminally truncated form Scf. Scf is a nuclear protein that introduces negative supercoils into DNA in conjunction with topoisomerase II. DCB45 is an endoplasmic reticulum-resident protein. | 0.603 |
| Timp | CG9876 | FBpp0081722 | FBpp0071889 | Tissue inhibitor of metalloproteinase; Metalloproteinase inhibitor that acts on both matrix metalloproteinases Mmp1 and Mmp2 in vitro. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor (By similarity). Required for wing maturation which is the final step in morphogenesis of the adult fly. Involved in the negative regulation of developmental tissue invasion for imaginal disk eversion during metamorphosis by inhibiting Mmp-mediated basement membrane (BM) degradation. Required for oogenesis and for the long-term maintainance of [...] | FI01017p; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. | 0.728 |
| Timp | mfas | FBpp0081722 | FBpp0081972 | Tissue inhibitor of metalloproteinase; Metalloproteinase inhibitor that acts on both matrix metalloproteinases Mmp1 and Mmp2 in vitro. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor (By similarity). Required for wing maturation which is the final step in morphogenesis of the adult fly. Involved in the negative regulation of developmental tissue invasion for imaginal disk eversion during metamorphosis by inhibiting Mmp-mediated basement membrane (BM) degradation. Required for oogenesis and for the long-term maintainance of [...] | Midline fasciclin, isoform J; Midline fasciclin (mfas) encodes a protein involved in axonogenesis and regulation of hemocyte proliferation. | 0.741 |
| Timp | net | FBpp0081722 | FBpp0288762 | Tissue inhibitor of metalloproteinase; Metalloproteinase inhibitor that acts on both matrix metalloproteinases Mmp1 and Mmp2 in vitro. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor (By similarity). Required for wing maturation which is the final step in morphogenesis of the adult fly. Involved in the negative regulation of developmental tissue invasion for imaginal disk eversion during metamorphosis by inhibiting Mmp-mediated basement membrane (BM) degradation. Required for oogenesis and for the long-term maintainance of [...] | Net, isoform B; Net (net) encodes a basic helix-loop-helix protein that probably acts as a transcriptional repressor. During wing vein formation it is expressed in all interveins territories and antagonises the activity of the product of Egfr. | 0.584 |
| Timp | scf | FBpp0081722 | FBpp0088881 | Tissue inhibitor of metalloproteinase; Metalloproteinase inhibitor that acts on both matrix metalloproteinases Mmp1 and Mmp2 in vitro. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor (By similarity). Required for wing maturation which is the final step in morphogenesis of the adult fly. Involved in the negative regulation of developmental tissue invasion for imaginal disk eversion during metamorphosis by inhibiting Mmp-mediated basement membrane (BM) degradation. Required for oogenesis and for the long-term maintainance of [...] | Supercoiling factor (scf) encodes two polypeptides: DCB45 and its N-teminally truncated form Scf. Scf is a nuclear protein that introduces negative supercoils into DNA in conjunction with topoisomerase II. DCB45 is an endoplasmic reticulum-resident protein. | 0.736 |
| Timp | zetaCOP | FBpp0081722 | FBpp0075111 | Tissue inhibitor of metalloproteinase; Metalloproteinase inhibitor that acts on both matrix metalloproteinases Mmp1 and Mmp2 in vitro. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor (By similarity). Required for wing maturation which is the final step in morphogenesis of the adult fly. Involved in the negative regulation of developmental tissue invasion for imaginal disk eversion during metamorphosis by inhibiting Mmp-mediated basement membrane (BM) degradation. Required for oogenesis and for the long-term maintainance of [...] | Coatomer subunit zeta; The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. | 0.520 |
| Uggt | mfas | FBpp0074831 | FBpp0081972 | UDP-glucose-glycoprotein glucosyltransferase (Uggt) encodes an enzyme that recognizes glycoproteins with folding defects and adds glucose to N-glycans near the misfolded part of the protein. Uggt product is a component of the calnexin cycle and promotes protein folding in the endoplasmic reticulum along with the protein encoded by Cnx99A and Calr; Belongs to the glycosyltransferase 8 family. | Midline fasciclin, isoform J; Midline fasciclin (mfas) encodes a protein involved in axonogenesis and regulation of hemocyte proliferation. | 0.658 |
| lms | mfas | FBpp0309584 | FBpp0081972 | Lateral muscles scarcer, isoform B; Lateral muscles scarcer (lms) encodes a homeodomain transcription factor that is an identity factor for lateral transverse muscles. | Midline fasciclin, isoform J; Midline fasciclin (mfas) encodes a protein involved in axonogenesis and regulation of hemocyte proliferation. | 0.557 |
| mfas | CG9876 | FBpp0081972 | FBpp0071889 | Midline fasciclin, isoform J; Midline fasciclin (mfas) encodes a protein involved in axonogenesis and regulation of hemocyte proliferation. | FI01017p; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated. | 0.760 |
| mfas | Cog6 | FBpp0081972 | FBpp0087676 | Midline fasciclin, isoform J; Midline fasciclin (mfas) encodes a protein involved in axonogenesis and regulation of hemocyte proliferation. | Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function; Belongs to the COG6 family. | 0.511 |
| mfas | GC | FBpp0081972 | FBpp0072701 | Midline fasciclin, isoform J; Midline fasciclin (mfas) encodes a protein involved in axonogenesis and regulation of hemocyte proliferation. | Gamma-glutamyl carboxylase (GC) encodes an enzyme involved in peptidyl-glutamic acid carboxylation. | 0.562 |
| mfas | Timp | FBpp0081972 | FBpp0081722 | Midline fasciclin, isoform J; Midline fasciclin (mfas) encodes a protein involved in axonogenesis and regulation of hemocyte proliferation. | Tissue inhibitor of metalloproteinase; Metalloproteinase inhibitor that acts on both matrix metalloproteinases Mmp1 and Mmp2 in vitro. Complexes with metalloproteinases and irreversibly inactivates them by binding to their catalytic zinc cofactor (By similarity). Required for wing maturation which is the final step in morphogenesis of the adult fly. Involved in the negative regulation of developmental tissue invasion for imaginal disk eversion during metamorphosis by inhibiting Mmp-mediated basement membrane (BM) degradation. Required for oogenesis and for the long-term maintainance of [...] | 0.741 |
| mfas | Uggt | FBpp0081972 | FBpp0074831 | Midline fasciclin, isoform J; Midline fasciclin (mfas) encodes a protein involved in axonogenesis and regulation of hemocyte proliferation. | UDP-glucose-glycoprotein glucosyltransferase (Uggt) encodes an enzyme that recognizes glycoproteins with folding defects and adds glucose to N-glycans near the misfolded part of the protein. Uggt product is a component of the calnexin cycle and promotes protein folding in the endoplasmic reticulum along with the protein encoded by Cnx99A and Calr; Belongs to the glycosyltransferase 8 family. | 0.658 |
