STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG10005RE59626p. (231 aa)    
Predicted Functional Partners:
nyo
Nyobe, isoform C; It is involved in the biological process described with: apical constriction; regulation of embryonic cell shape.
   
  
 0.907
mey
Morpheyus, isoform A; It is involved in the biological process described with: apical constriction; regulation of embryonic cell shape.
   
  
 0.896
tyn
Trynity, isoform A; Trynity (tyn) encodes a protein belonging to the ZP-domain proteins family known as extracellular modular proteins. These proteins are secreted and anchored to the membrane or released into the extracellular space to form specialized extracellular matrices.
   
  
 0.892
dyl
Dusky-like, isoform A; Dusky-like (dyl) encodes a plasma membrane protein involved in actin filament organization. It is involved in apical constriction, cell-matrix adhesion and hair morphogenesis.
   
  
 0.836
z
Regulatory protein zeste; Zeste (z) encodes a sequence-specific DNA-binding protein. It is often found in the proximal promoter region of many genes where it helps to recruit the BRM nucleosome remodeling complex. It is best known for the pairing-dependent repressive effects produced by some of its mutants on target genes, especially the w gene.
      
 0.670
CG34205
Uncharacterized protein; RNA polymerase II cis-regulatory region sequence-specific DNA binding; transcription coactivator activity; RNA polymerase II core promoter sequence-specific DNA binding. It is involved in the biological process described with: positive regulation of transcription by RNA polymerase II.
      
 0.602
CG14257
IP12874p.
      
 0.601
Cpr76Bc
Cuticular protein 76Bc, isoform C; Structural constituent of cuticle; structural constituent of chitin-based larval cuticle. It is involved in the biological process described with: chitin-based cuticle development.
      
 0.601
dsx-c73A
Doublesex cognate 73A (dsx-c73A) encodes a secreted cuticle protein present in the epidermis, salivary duct and trachea. The epidermal expression is under the control of the product of ovo.
   
  
 0.451
CG34461
GEO11286p1; Structural constituent of chitin-based cuticle; structural constituent of chitin-based larval cuticle. It is involved in the biological process described with: chitin-based cuticle development.
      
 0.430
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.