STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mthl5Methuselah-like 5 (mthl5) encodes a G protein-coupled receptor involved in heart morphogenesis. (497 aa)    
Predicted Functional Partners:
mthl14
Probable G-protein coupled receptor Mth-like 14; G protein-coupled receptor activity. It is involved in the biological process described with: G protein-coupled receptor signaling pathway.
      
 0.910
CG6962
LD28817p; Sphingomyelin phosphodiesterase D activity. It is involved in the biological process described with: ceramide biosynthetic process; glycerophospholipid catabolic process; sphingomyelin catabolic process.
      
 0.836
mthl7
Probable G-protein coupled receptor Mth-like 7; G protein-coupled receptor activity. It is involved in the biological process described with: determination of adult lifespan; cell surface receptor signaling pathway; G protein-coupled receptor signaling pathway; response to starvation; Belongs to the G-protein coupled receptor 2 family. Mth subfamily.
      
 0.672
CG31368
Uncharacterized protein, isoform D; mRNA binding; RNA binding. It is involved in the biological process described with: mRNA splicing, via spliceosome.
      
 0.665
ng4
Protein new-glue 4.
      
 0.658
mthl13
Methuselah-like 13; G protein-coupled receptor activity. It is involved in the biological process described with: cell surface receptor signaling pathway; G protein-coupled receptor signaling pathway.
      
 0.608
mthl12
Probable G-protein coupled receptor Mth-like 12; G protein-coupled receptor activity. It is involved in the biological process described with: determination of adult lifespan; cell surface receptor signaling pathway; G protein-coupled receptor signaling pathway; response to starvation.
      
 0.604
mthl6
Probable G-protein coupled receptor Mth-like 6; G protein-coupled receptor activity. It is involved in the biological process described with: G protein-coupled receptor signaling pathway; response to starvation; cell surface receptor signaling pathway; determination of adult lifespan.
      
 0.603
Cirl
Latrophilin Cirl; Latrotoxin receptor activity; G protein-coupled receptor activity; carbohydrate binding; Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
   
 
 0.530
Galphao
G protein alpha o subunit (Galphao) encodes the most abundant G protein in the nervous tissue and is involved in signaling by a variety of GPCRs. It contributes to heart development, axonogenesis, neuro-muscular junction formation, asymmetric cell division, planar cell polarity, blood-brain barrier establishment, Wnt signaling, and gustatory and olfactory sensory perception; Belongs to the G-alpha family. G(i/o/t/z) subfamily.
    
 
 0.528
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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