ssp5 protein (Drosophila melanogaster) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ssp5

Short spindle 5. (711 aa)

Predicted Functional Partners:

CG5089

0.929

ssp2

0.918

mei-38

0.913

ssp3

0.912

CG4691

0.840

CG4983

0.826

CG4669

0.824

vrs

0.820

CG8701

0.820

Hsp60B

0.819

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly

Export your current network:

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CG4669	CG4691	FBpp0076874	FBpp0080232	FI09606p.	GH20441p.	0.820
CG4669	CG4983	FBpp0076874	FBpp0309457	FI09606p.	GH17939p.	0.823
CG4669	CG5089	FBpp0076874	FBpp0086253	FI09606p.	GH06435p.	0.819
CG4669	CG8701	FBpp0076874	FBpp0087819	FI09606p.	GH07855p.	0.820
CG4669	Hsp60B	FBpp0076874	FBpp0077665	FI09606p.	60 kDa heat shock protein homolog 1, mitochondrial; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family.	0.794
CG4669	ssp5	FBpp0076874	FBpp0082012	FI09606p.	Short spindle 5.	0.824
CG4669	vrs	FBpp0076874	FBpp0082100	FI09606p.	GH03227p; It is involved in the biological process described with: chromatin organization.	0.812
CG4691	CG4669	FBpp0080232	FBpp0076874	GH20441p.	FI09606p.	0.820
CG4691	CG4983	FBpp0080232	FBpp0309457	GH20441p.	GH17939p.	0.968
CG4691	CG5089	FBpp0080232	FBpp0086253	GH20441p.	GH06435p.	0.999
CG4691	CG8701	FBpp0080232	FBpp0087819	GH20441p.	GH07855p.	0.999
CG4691	Hsp60B	FBpp0080232	FBpp0077665	GH20441p.	60 kDa heat shock protein homolog 1, mitochondrial; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family.	0.831
CG4691	ssp5	FBpp0080232	FBpp0082012	GH20441p.	Short spindle 5.	0.840
CG4691	vrs	FBpp0080232	FBpp0082100	GH20441p.	GH03227p; It is involved in the biological process described with: chromatin organization.	0.974
CG4983	CG4669	FBpp0309457	FBpp0076874	GH17939p.	FI09606p.	0.823
CG4983	CG4691	FBpp0309457	FBpp0080232	GH17939p.	GH20441p.	0.968
CG4983	CG5089	FBpp0309457	FBpp0086253	GH17939p.	GH06435p.	0.831
CG4983	CG8701	FBpp0309457	FBpp0087819	GH17939p.	GH07855p.	0.832
CG4983	Hsp60B	FBpp0309457	FBpp0077665	GH17939p.	60 kDa heat shock protein homolog 1, mitochondrial; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family.	0.810
CG4983	ssp5	FBpp0309457	FBpp0082012	GH17939p.	Short spindle 5.	0.826