STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dpr17Defective proboscis extension response 17, isoform A; It is involved in the biological process described with: sensory perception of chemical stimulus; synapse organization. (664 aa)    
Predicted Functional Partners:
DIP-gamma
Dpr-interacting protein gamma (DIP-gamma) encodes a single-pass membrane protein expressed in the larval ventral nerve chord and pupal and adult optic lobe. It is required for synaptic development and survival, and interacts with the product of dpr11 to guide synaptic connectivity in the optic lobe.
    
 
0.727
DIP-theta
Dpr-interacting protein theta; It is involved in the biological process described with: synapse organization.
  
  
0.632
DIP-epsilon
Dpr-interacting protein epsilon; It is involved in the biological process described with: synapse organization.
    
 
0.628
CG4702
Uncharacterized protein, isoform B.
    
 
 0.611
side-III
Sidestep III, isoform O.
    
 
 0.570
rdo
Reduced ocelli (rdo) encodes a transmembrane leucine rich repeat protein involved in ocelli development.
    
 
 0.528
beat-IIb
Beaten path IIb, isoform A; It is involved in the biological process described with: motor neuron axon guidance; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules.
      
 0.495
CG1958
GH24548p.
   
  
 0.482
dpr16
Defective proboscis extension response 16, isoform C; It is involved in the biological process described with: synapse organization; sensory perception of chemical stimulus.
      
0.479
otk
Tyrosine-protein kinase-like otk; Acts as a calcium-dependent, homophilic cell adhesion molecule that regulates neural recognition during the development of the nervous system. Component of the repulsive Plexin signaling response to regulate motor axon guidance at the embryonic stage. Also component of a receptor complex that is required in the adult visual system to innervate the lamina layer; specific targeting of R1-R6 axons; Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
    
 
 0.476
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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