Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
dpr17Defective proboscis extension response 17, isoform A; It is involved in the biological process described with: sensory perception of chemical stimulus; synapse organization. (664 aa)    
Predicted Functional Partners:
DIP-gamma
Dpr-interacting protein gamma (DIP-gamma) encodes a single-pass membrane protein expressed in the larval ventral nerve chord and pupal and adult optic lobe. It is required for synaptic development and survival, and interacts with the product of dpr11 to guide synaptic connectivity in the optic lobe.
   
 
0.938
DIP-epsilon
Dpr-interacting protein epsilon; It is involved in the biological process described with: synapse organization.
    
 
0.858
CG4702
Uncharacterized protein, isoform B.
      
 0.593
CG7194
IP12463p; It is involved in the biological process described with: copper ion homeostasis.
    
 
 0.543
side-III
Sidestep III, isoform O.
      
 0.520
rdo
Reduced ocelli (rdo) encodes a transmembrane leucine rich repeat protein involved in ocelli development.
   
 
 0.479
CG1958
GH24548p.
   
  
 0.449
CG14502
LD04457p.
      
 0.425
CG42458
RRM domain-containing protein; mRNA binding; RNA binding.
      
 0.422
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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