STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG3916Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. (267 aa)    
Predicted Functional Partners:
mey
Morpheyus, isoform A; It is involved in the biological process described with: apical constriction; regulation of embryonic cell shape.
    
 
 0.798
nyo
Nyobe, isoform C; It is involved in the biological process described with: apical constriction; regulation of embryonic cell shape.
    
 
 0.794
CG6800
Cyclin-dependent protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: protein phosphorylation.
   
  
 0.677
Lcp65Ab2
Larval cuticle protein 65Ab1; Component of the cuticle of the larva.
      
 0.664
Fur1
Furin-like protease 1, isoforms 1/1-X/2; Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif.
     
 0.663
Vha100-4
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
      
 0.661
Vha100-2
V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
      
 0.628
Lcp3
Larval cuticle protein 3; Component of the larval cuticle.
   
  
 0.551
CG15073
FI04829p; DNA-binding transcription factor activity; zinc ion binding; transcription regulatory region sequence-specific DNA binding. It is involved in the biological process described with: regulation of transcription, DNA-templated; regulation of gene expression.
      
 0.523
CG13527
Uncharacterized protein, isoform B; It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
     0.519
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.