| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Cpr65Ec | Cyp313a4 | FBpp0076618 | FBpp0082136 | Cuticular protein 65Ec; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development. | Probable cytochrome P450 313a4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.521 |
| Cpr65Ec | GstE10 | FBpp0076618 | FBpp0310604 | Cuticular protein 65Ec; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development. | Glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process; Belongs to the GST superfamily. | 0.493 |
| Cpr65Ec | alpha-Est10 | FBpp0076618 | FBpp0297077 | Cuticular protein 65Ec; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development. | Carboxylic ester hydrolase activity; Belongs to the type-B carboxylesterase/lipase family. | 0.524 |
| Cyp12b2 | Cyp308a1 | FBpp0085792 | FBpp0074375 | Probable cytochrome P450 12b2, mitochondrial; Heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. It is involved in the biological process described with: oxidation-reduction process; Belongs to the cytochrome P450 family. | Probable cytochrome P450 308a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.447 |
| Cyp12b2 | Cyp313a4 | FBpp0085792 | FBpp0082136 | Probable cytochrome P450 12b2, mitochondrial; Heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. It is involved in the biological process described with: oxidation-reduction process; Belongs to the cytochrome P450 family. | Probable cytochrome P450 313a4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.447 |
| Cyp12c1 | Cyp308a1 | FBpp0311798 | FBpp0074375 | Probable cytochrome P450 12c1, mitochondrial; Heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; Belongs to the cytochrome P450 family. | Probable cytochrome P450 308a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.412 |
| Cyp12c1 | Cyp313a4 | FBpp0311798 | FBpp0082136 | Probable cytochrome P450 12c1, mitochondrial; Heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; Belongs to the cytochrome P450 family. | Probable cytochrome P450 313a4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.466 |
| Cyp304a1 | Cyp313a4 | FBpp0082159 | FBpp0082136 | Probable cytochrome P450 304a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Probable cytochrome P450 313a4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.544 |
| Cyp308a1 | Cyp12b2 | FBpp0074375 | FBpp0085792 | Probable cytochrome P450 308a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Probable cytochrome P450 12b2, mitochondrial; Heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. It is involved in the biological process described with: oxidation-reduction process; Belongs to the cytochrome P450 family. | 0.447 |
| Cyp308a1 | Cyp12c1 | FBpp0074375 | FBpp0311798 | Probable cytochrome P450 308a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Probable cytochrome P450 12c1, mitochondrial; Heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; Belongs to the cytochrome P450 family. | 0.412 |
| Cyp308a1 | Cyp313a4 | FBpp0074375 | FBpp0082136 | Probable cytochrome P450 308a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Probable cytochrome P450 313a4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.480 |
| Cyp308a1 | phm | FBpp0074375 | FBpp0309669 | Probable cytochrome P450 308a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Phantom (phm) encodes a cytochrome P450 involved in ecdysteroid biosynthesis. It is an endoplasmic reticulum protein that catalyzes the addition of a hydroxyl group to the 25 carbon of the cholesterol side chain. phm mutants fail to undergo head involution, dorsal closure and cuticle secretion. | 0.400 |
| Cyp308a1 | sad | FBpp0074375 | FBpp0081949 | Probable cytochrome P450 308a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Shadow (sad) encodes a cytochrome P450 involved in ecdysteroid biosynthesis. It shows a mitochondrial localization and catalyzes the addition of a hydroxyl group to the 2 carbon of the cholesterol ring. sad mutants fail to undergo head involution, dorsal closure or to secrete cuticle. | 0.691 |
| Cyp308a1 | shd | FBpp0074375 | FBpp0305245 | Probable cytochrome P450 308a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Ecdysone 20-monooxygenase; Shade (shd) encodes 20-hydroxylase and is responsible for converting Ecdysone into 20-hydroxyecdysone, the active form of the steroid. It is required in all tissues that produce active Ecdysone and thus contributes to larval moulting, metamorphosis, growth, neuroblast diversity and egg chamber maturation; Belongs to the cytochrome P450 family. | 0.537 |
| Cyp313a4 | Cpr65Ec | FBpp0082136 | FBpp0076618 | Probable cytochrome P450 313a4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Cuticular protein 65Ec; Structural constituent of chitin-based larval cuticle; structural constituent of cuticle. It is involved in the biological process described with: chitin-based cuticle development. | 0.521 |
| Cyp313a4 | Cyp12b2 | FBpp0082136 | FBpp0085792 | Probable cytochrome P450 313a4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Probable cytochrome P450 12b2, mitochondrial; Heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. It is involved in the biological process described with: oxidation-reduction process; Belongs to the cytochrome P450 family. | 0.447 |
| Cyp313a4 | Cyp12c1 | FBpp0082136 | FBpp0311798 | Probable cytochrome P450 313a4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Probable cytochrome P450 12c1, mitochondrial; Heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; iron ion binding. It is involved in the biological process described with: oxidation-reduction process; Belongs to the cytochrome P450 family. | 0.466 |
| Cyp313a4 | Cyp304a1 | FBpp0082136 | FBpp0082159 | Probable cytochrome P450 313a4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Probable cytochrome P450 304a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.544 |
| Cyp313a4 | Cyp308a1 | FBpp0082136 | FBpp0074375 | Probable cytochrome P450 313a4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Probable cytochrome P450 308a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.480 |
| Cyp313a4 | GstE10 | FBpp0082136 | FBpp0310604 | Probable cytochrome P450 313a4; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Glutathione transferase activity. It is involved in the biological process described with: glutathione metabolic process; Belongs to the GST superfamily. | 0.491 |