STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
d-cupDavis-cup; Calcium ion binding. (219 aa)    
Predicted Functional Partners:
CG13373
Uncharacterized protein, isoform B.
    
 
 0.840
CG17290
RE15976p.
      
 0.836
schuy
Schumacher-levy.
   
  
 0.824
hale
Hale-bopp.
   
  
 0.811
t-cup
Tetleys-cup; Belongs to the cytochrome b5 family.
   
  
 0.809
PIG-S
Phosphatidylinositol glycan anchor biosynthesis class S (PIG-S) encodes a subunit of glycosylphosphatidylinositol (GPI) transamidase, which mediates GPI anchoring in the endoplasmic reticulum. GPI anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane.
    
 
 0.790
f-cup
Flyers-cup, isoform F.
   
 
 0.710
sud1
Sudestada1 (sud1) encodes a prolyl hydroxylase that modifies a specific prolyl residue of the small ribosomal subunit protein encoded by RpS23. Lack of sud1 affects growth, triggers the unfolded protein response, as well as apoptosis and autophagy; Belongs to the TPA1 family.
    
 
 0.680
CG15649
IP05660p.
   
 
 0.678
CASK
Peripheral plasma membrane protein CASK; CASK (CASK) encodes a member of the MAGUK family of scaffolding proteins. In epithelial tissues, the product of CASK functions as an adhesion molecule involved in cell proliferation, cytoskeletal remodeling and cell migration. In neurons, the product of CASK serves as a scaffold for a number of signaling and transmembrane molecules and is involved in synaptic development and plasticity.
    
 
 0.676
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.