Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
d-cupDavis-cup; Calcium ion binding. (219 aa)    
Predicted Functional Partners:
schuy
Schumacher-levy.
   
  
 0.845
hale
Hale-bopp.
   
  
 0.836
CG13373
Uncharacterized protein, isoform B.
    
 
 0.829
CG17290
RE15976p.
      
 0.829
PIG-S
Phosphatidylinositol glycan anchor biosynthesis class S (PIG-S) encodes a subunit of glycosylphosphatidylinositol (GPI) transamidase, which mediates GPI anchoring in the endoplasmic reticulum. GPI anchor attachment serves as a general mechanism for linking proteins to the cell surface membrane.
      
 0.780
t-cup
Tetleys-cup; Belongs to the cytochrome b5 family.
   
  
 0.765
sud1
Sudestada1 (sud1) encodes a prolyl hydroxylase that modifies a specific prolyl residue of the small ribosomal subunit protein encoded by RpS23. Lack of sud1 affects growth, triggers the unfolded protein response, as well as apoptosis and autophagy; Belongs to the TPA1 family.
      
 0.743
f-cup
Flyers-cup, isoform F.
   
 
 0.684
CG15649
IP05660p.
   
  
 0.674
koko
Kokopelli, isoform B; Cyclin-dependent protein serine/threonine kinase regulator activity. It is involved in the biological process described with: regulation of transcription by RNA polymerase II.
      
 0.653
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.