STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG9288Protein Abitram; May regulate actin polymerization. (214 aa)    
Predicted Functional Partners:
CG3709
Putative tRNA pseudouridine synthase Pus10; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase Pus10 family.
   
   0.783
CG2656
GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.
   
    0.649
tun
Protein N-terminal glutamine amidohydrolase; Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Belongs to the NTAQ1 family.
      
 0.608
Pex6
Peroxin 6, isoform D; ATP binding; ATPase activity. It is involved in the biological process described with: peroxisome organization; protein import into peroxisome matrix; protein targeting to peroxisome.
   
  
 0.500
mRpS21
Mitochondrial ribosomal protein S21, isoform A; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation.
   
    0.447
alpha-Catr
Alpha-catenin related, isoform C; Actin filament binding. It is involved in the biological process described with: cell adhesion; Rho protein signal transduction.
      
 0.426
CG15715
MIP04739p.
   
  
 0.420
MED18
Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
   
    0.415
CG7785
RE37682p.
   
  
 0.414
CG4325
Ubiquitin protein ligase activity; zinc ion binding. It is involved in the biological process described with: intracellular signal transduction; positive regulation of antibacterial peptide biosynthetic process; protein ubiquitination.
   
   0.409
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.