Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG9286Protein BCCIP homolog; Protein kinase regulator activity; tubulin binding; kinase regulator activity; Belongs to the BCP1 family. (297 aa)    
Predicted Functional Partners:
eIF6
Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
   
 
 0.950
RpL23
60S ribosomal protein L23; Large ribosomal subunit rRNA binding; structural constituent of ribosome; myosin binding. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uL14 family.
   
 
 0.938
CG1542
Probable rRNA-processing protein EBP2 homolog; Required for the processing of the 27S pre-rRNA. Belongs to the EBP2 family.
   
  
 0.921
Non3
Ribosome production factor 2 homolog; Required for normal assembly of the mitotic spindle. May be involved in both centrosome-dependent and centrosome-independent spindle assembly programs; Belongs to the RPF2 family.
   
  
 0.884
CG46385
Uncharacterized protein, isoform E; RNA adenylyltransferase activity. It is involved in the biological process described with: mRNA stabilization.
    
 
 0.884
CG11752
RH44935p.
   
  
 0.880
CG11920
FI08810p; snoRNA binding. It is involved in the biological process described with: rRNA processing.
   
    0.849
CG12909
CG12909 protein; DNA binding. It is involved in the biological process described with: rRNA processing; negative regulation of transcription by RNA polymerase II.
   
  
 0.847
CG11583
Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family.
   
    0.843
CG6937
RRM domain-containing protein; mRNA binding; RNA binding. It is involved in the biological process described with: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
    0.839
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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