| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CG11674 | CG9925 | FBpp0073743 | FBpp0082339 | LD24340p. | RE70955p; It is involved in the biological process described with: positive regulation of innate immune response; defense response to Gram-negative bacterium. | 0.692 |
| CG11674 | dhd | FBpp0073743 | FBpp0311766 | LD24340p. | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | 0.840 |
| CG11674 | gnu | FBpp0073743 | FBpp0075447 | LD24340p. | CG5272 protein; Giant nuclei (gnu) encodes a regulatory subunit of the PNG kinase complex, which regulates the levels of the protein encoded by CycB. Members of this complex are required maternally for the normal nuclear divisions of the syncytial embryo. | 0.845 |
| CG11674 | mtrm | FBpp0073743 | FBpp0076340 | LD24340p. | Protein matrimony; Polo kinase inhibitor required to maintain G2 arrest in the meiotic cell cycle in females. Holds heterochromatically paired homologs together from the end of pachytene until metaphase I. Haploinsufficient locus for homologous achiasmate segregation and may be required for the maintenance of heterochromatic pairings. | 0.909 |
| CG11674 | osk | FBpp0073743 | FBpp0081435 | LD24340p. | Maternal effect protein oskar; Organizes the germ plasm and directs localization of the posterior determinant nanos. Oskar protein is required to keep nos RNA and staufen protein at the posterior pole. | 0.883 |
| CG11674 | piwi | FBpp0073743 | FBpp0079755 | LD24340p. | Protein piwi; Acts via the piwi-interacting RNA (piRNA) metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. In ovarian somatic cells, mediates silencing of transposable elements at the transcriptional level in a mael-dependent manner. [...] | 0.464 |
| CG11674 | zpg | FBpp0073743 | FBpp0303218 | LD24340p. | Innexin inx4; Structural component of the gap junctions in germline cells. Required for differentiation and survival of germline cysts in females and of spermatogonia in males; gap junctional communication between spermatogonia and somatic cyst cells may be required for normal differentiation and survival of spermatogonia. Belongs to the pannexin family. | 0.850 |
| CG9925 | CG11674 | FBpp0082339 | FBpp0073743 | RE70955p; It is involved in the biological process described with: positive regulation of innate immune response; defense response to Gram-negative bacterium. | LD24340p. | 0.692 |
| CG9925 | dhd | FBpp0082339 | FBpp0311766 | RE70955p; It is involved in the biological process described with: positive regulation of innate immune response; defense response to Gram-negative bacterium. | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | 0.689 |
| CG9925 | gnu | FBpp0082339 | FBpp0075447 | RE70955p; It is involved in the biological process described with: positive regulation of innate immune response; defense response to Gram-negative bacterium. | CG5272 protein; Giant nuclei (gnu) encodes a regulatory subunit of the PNG kinase complex, which regulates the levels of the protein encoded by CycB. Members of this complex are required maternally for the normal nuclear divisions of the syncytial embryo. | 0.687 |
| CG9925 | krimp | FBpp0082339 | FBpp0086333 | RE70955p; It is involved in the biological process described with: positive regulation of innate immune response; defense response to Gram-negative bacterium. | FI20010p1; Metal ion binding. It is involved in the biological process described with: oocyte dorsal/ventral axis specification; negative regulation of oskar mRNA translation; oocyte karyosome formation. | 0.817 |
| CG9925 | mtrm | FBpp0082339 | FBpp0076340 | RE70955p; It is involved in the biological process described with: positive regulation of innate immune response; defense response to Gram-negative bacterium. | Protein matrimony; Polo kinase inhibitor required to maintain G2 arrest in the meiotic cell cycle in females. Holds heterochromatically paired homologs together from the end of pachytene until metaphase I. Haploinsufficient locus for homologous achiasmate segregation and may be required for the maintenance of heterochromatic pairings. | 0.735 |
| CG9925 | osk | FBpp0082339 | FBpp0081435 | RE70955p; It is involved in the biological process described with: positive regulation of innate immune response; defense response to Gram-negative bacterium. | Maternal effect protein oskar; Organizes the germ plasm and directs localization of the posterior determinant nanos. Oskar protein is required to keep nos RNA and staufen protein at the posterior pole. | 0.689 |
| CG9925 | piwi | FBpp0082339 | FBpp0079755 | RE70955p; It is involved in the biological process described with: positive regulation of innate immune response; defense response to Gram-negative bacterium. | Protein piwi; Acts via the piwi-interacting RNA (piRNA) metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. In ovarian somatic cells, mediates silencing of transposable elements at the transcriptional level in a mael-dependent manner. [...] | 0.904 |
| CG9925 | spn-E | FBpp0082339 | FBpp0082637 | RE70955p; It is involved in the biological process described with: positive regulation of innate immune response; defense response to Gram-negative bacterium. | Probable ATP-dependent RNA helicase spindle-E; Probable ATP-binding RNA helicase which plays a central role during spermatogenesis and oogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi and govern the methylation and subsequent repression of transposons. Involved in the repression of LTR retrotransposon copia. Also involved in telomere regulation by repres [...] | 0.797 |
| CG9925 | tej | FBpp0082339 | FBpp0086689 | RE70955p; It is involved in the biological process described with: positive regulation of innate immune response; defense response to Gram-negative bacterium. | FI02030p; It is involved in the biological process described with: negative regulation of transposition; piRNA biosynthetic process; oocyte karyosome formation. | 0.730 |
| CG9925 | zpg | FBpp0082339 | FBpp0303218 | RE70955p; It is involved in the biological process described with: positive regulation of innate immune response; defense response to Gram-negative bacterium. | Innexin inx4; Structural component of the gap junctions in germline cells. Required for differentiation and survival of germline cysts in females and of spermatogonia in males; gap junctional communication between spermatogonia and somatic cyst cells may be required for normal differentiation and survival of spermatogonia. Belongs to the pannexin family. | 0.750 |
| dhd | CG11674 | FBpp0311766 | FBpp0073743 | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | LD24340p. | 0.840 |
| dhd | CG9925 | FBpp0311766 | FBpp0082339 | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | RE70955p; It is involved in the biological process described with: positive regulation of innate immune response; defense response to Gram-negative bacterium. | 0.689 |
| dhd | gnu | FBpp0311766 | FBpp0075447 | Thioredoxin-1; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. As a reducing substrate of peroxiredoxin 1, thioredoxin 2 is preferred over thioredoxin 1. Required for female meiosis and early embryonic development. | CG5272 protein; Giant nuclei (gnu) encodes a regulatory subunit of the PNG kinase complex, which regulates the levels of the protein encoded by CycB. Members of this complex are required maternally for the normal nuclear divisions of the syncytial embryo. | 0.967 |