STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG3505CLIP domain-containing serine protease; It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family. CLIP subfamily. (360 aa)    
Predicted Functional Partners:
CG5390
FI06461p; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
  
0.565
fat-spondin
Fat-spondin; Serine-type endopeptidase inhibitor activity. It is involved in the biological process described with: cell adhesion.
   
  
 0.540
Sems
Seminase (Sems) encodes a serine protease produced in male's accessory glands and transferred to females during mating. It is an essential component in the pathway for proteolytic processing of different seminal proteins. It cleaves the metalloprotease encoded by Semp1, which in turn also cleaves the seminal proteins encoded by Acp26Aa and Acp36DE. It is also required for sperm release from storage via regulation of the product of SP.
  
     0.518
Jon25Biii
Jonah 25Biii; Serine-type endopeptidase activity; endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
     0.518
Idgf5
Chitinase-like protein Idgf5; Probably required to stimulate the proliferation, polarization and motility of imaginal disk cells. May act by stabilizing the binding of insulin-like peptides to its receptor through a simultaneous interaction with both molecules to form a multiprotein signaling complex (By similarity); Belongs to the glycosyl hydrolase 18 family. IDGF subfamily.
   
  
 0.516
Jon66Ci
Jonah 66Ci; Serine-type endopeptidase activity; endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
     0.510
CG32277
Peptidase S1 domain-containing protein; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
     0.509
CG13527
Uncharacterized protein, isoform B; It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
     0.497
CG8586
FI19801p1; Serine-type endopeptidase activity. It is involved in the biological process described with: proteolysis.
  
   
0.495
CG15873
Peptidase S1 domain-containing protein; It is involved in the biological process described with: proteolysis; Belongs to the peptidase S1 family.
  
     0.456
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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