STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG3631Glycosaminoglycan xylosylkinase homolog; Kylose kinase that mediates the 2-O-phosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans. Belongs to the FAM20 family. (421 aa)    
Predicted Functional Partners:
fj
Extracellular serine/threonine protein kinase four-jointed; Golgi serine/threonine protein kinase required for intermediate growth in the proximal-distal axis. Phosphorylates specific residues within extracellular cadherin domains of Fat (ft) and Dachsous (ds) as they transit through the Golgi. Acts in ommatidial polarity determination as a secondary signal downstream of Notch, JAK/STAT and wingless. Also necessary for the initiation, up- regulation or maintenance of Notch ligand, Serrate (Ser) expression in legs, thereby participating in a feedback loop with N signaling. Sufficient fo [...]
      
 0.755
CG11539
N-acetyltransferase 9-like protein; Transferase activity, transferring acyl groups other than amino-acyl groups. It is involved in the biological process described with: protein acetylation; histone acetylation; Belongs to the acetyltransferase family. GNAT subfamily.
 
      0.724
Cpr
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome p450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome b5 (By similarity). May function to clear the olfactory organ (antennae) from accumulating chemicals. In the N-terminal section; belongs to the flavodoxin family.
 
      0.712
CLIP-190
Restin homolog; Together CLIP-190 and jar may coordinate the interaction between the actin and microtubule cytoskeleton. May link endocytic vesicles to microtubules. May play a role in formation of furrows during cellularization.
      
 0.627
Glg1
Golgi complex-localized glycoprotein 1, isoform B; Fibroblast growth factor binding.
   
  
 0.609
CG9518
FI02019p; Flavin adenine dinucleotide binding; oxidoreductase activity, acting on CH-OH group of donors; oxidoreductase activity. It is involved in the biological process described with: ecdysteroid metabolic process; oxidation-reduction process; response to endoplasmic reticulum stress.
      
 0.608
CG2662
RE68603p; Chromatin binding; histone binding. It is involved in the biological process described with: negative regulation of transcription, DNA-templated.
   
  
 0.553
CG33932
GEO12594p1; It is involved in the biological process described with: cellular calcium ion homeostasis.
   
  
 0.550
Uxs
UDP-xylose synthase; NAD+ binding; UDP-glucuronate decarboxylase activity.
   
  
 0.543
CG14182
MIP13743p; It is involved in the biological process described with: negative regulation of smoothened signaling pathway.
   
  
 0.542
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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