Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
RpL10AaRibosomal protein L10Aa (RpL10Aa) encodes a component of the large ribosomal subunit. It is likely a retrogene derived from RpL10Ab and, unlike RpL10Ab, the expression of RpL10Aa is low in most tissues/developmental stages but enriched in the adult testis. (216 aa)    
Predicted Functional Partners:
RpL38
Ribosomal protein L38 (RpL38) encodes a component of the large subunit of cytoplasmic ribosomes, which translate mRNAs encoded by the nuclear genome. RpL38 is haploinsufficient - heterozygous mutants display the 'Minute' phenotype, characterized by a slower developmental rate and small adult bristles.
   
 
 0.991
RpL18A
60S ribosomal protein L18a; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eL20 family.
  
 
 0.990
RpS19a
Ribosomal protein S19a (RpS19a) encodes a structural constituent of ribosomes; Belongs to the eukaryotic ribosomal protein eS19 family.
  
 
 0.990
RpL37b
Probable 60S ribosomal protein L37-B; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family.
   
 
 0.989
RpL12
Ribosomal protein L12 (RpL12) encodes a protein of the large subunit of the ribosome. It regulates transcription of ribosomal proteins and ribosome biogenesis genes as well as interacting with the Enhancer of Trithorax and Polycomb protein encoded by corto.
  
 
 0.989
RpL17
60S ribosomal protein L17; Structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; Belongs to the universal ribosomal protein uL22 family.
  
 
 0.988
RpS25
40S ribosomal protein S25; Structural constituent of ribosome. It is involved in the biological process described with: cytoplasmic translation; Belongs to the eukaryotic ribosomal protein eS25 family.
   
 
 0.988
RpL4
60S ribosomal protein L4; Structural constituent of ribosome; RNA binding. It is involved in the biological process described with: cytoplasmic translation; translation; Belongs to the universal ribosomal protein uL4 family.
  
 
 0.988
RpS28a
Ribosomal protein S28a; Structural constituent of ribosome. It is involved in the biological process described with: ribosomal small subunit assembly; translation; wing disc development; maturation of SSU-rRNA; cytoplasmic translation.
   
 
 0.988
RpS11
40S ribosomal protein S11; Structural constituent of ribosome. It is involved in the biological process described with: translation; cytoplasmic translation; Belongs to the universal ribosomal protein uS17 family.
  
 
 0.988
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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