Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CG4338Probable ribosome biogenesis protein CG4338; Probable pre-rRNA processing protein involved in ribosome biogenesis. (274 aa)    
Predicted Functional Partners:
CG14543
RE68515p; It is involved in the biological process described with: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
  
 0.905
CG34195
Methyltransferase-like protein; tRNA (cytosine) methyltransferase activity. It is involved in the biological process described with: tRNA methylation; Belongs to the methyltransferase superfamily. METL family.
 
 
  
 0.899
mRpS28
Mitochondrial ribosomal protein S28; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; translation.
   
  
 0.850
mRpL17
Mitochondrial ribosomal protein L17, isoform A; Structural constituent of ribosome. It is involved in the biological process described with: translation; mitochondrial translation.
   
  
 0.830
PIP4K
Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) encodes an enzyme that mediates the conversion of phosphatidylinositol 4 phosphate to phosphatidylinositol 4,5 bisphosphate. It has been implicated in the regulation of mTOR signalling and control of cell size.
    
   0.829
Tsr1
Pre-rRNA-processing protein TSR1 homolog; Required during maturation of the 40S ribosomal subunit in the nucleolus; Belongs to the TRAFAC class translation factor GTPase superfamily. Bms1-like GTPase family. TSR1 subfamily.
   
  
 0.809
CG10050
RE31178p.
      
 0.793
CG2006
FI21859p1.
      
 0.793
mRpS26
Probable 28S ribosomal protein S26, mitochondrial; Structural constituent of ribosome. It is involved in the biological process described with: mitochondrial translation; Belongs to the mitochondrion-specific ribosomal protein mS26 family.
   
  
 0.777
CG10903
RE22146p; rRNA (guanine) methyltransferase activity. It is involved in the biological process described with: rRNA (guanine-N7)-methylation.
   
  
 0.768
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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