node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CG10340 | Sb | FBpp0082803 | FBpp0310459 | RE28913p; It is involved in the biological process described with: mitochondrial proton-transporting ATP synthase complex assembly. | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | 0.496 |
Cyp4c3 | Sb | FBpp0085074 | FBpp0310459 | Cytochrome P450 4c3; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | 0.497 |
La | P32 | FBpp0080906 | FBpp0086051 | La protein homolog; May be involved in transcription termination by RNA polymerase III. Binds RNA and DNA. Binds to precursors of RNA polymerase III transcripts. May play a specialized role during fly development. | CG6459 protein; P32 (P32) encodes an evolutionarily conserved mitochondrial protein that functions in presynaptic calcium signaling and neurotransmitter release as well as chromatin metabolism. | 0.834 |
La | Sb | FBpp0080906 | FBpp0310459 | La protein homolog; May be involved in transcription termination by RNA polymerase III. Binds RNA and DNA. Binds to precursors of RNA polymerase III transcripts. May play a specialized role during fly development. | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | 0.606 |
Oseg5 | Sb | FBpp0288481 | FBpp0310459 | Outer segment 5; It is involved in the biological process described with: non-motile cilium assembly; cilium assembly. | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | 0.481 |
P32 | La | FBpp0086051 | FBpp0080906 | CG6459 protein; P32 (P32) encodes an evolutionarily conserved mitochondrial protein that functions in presynaptic calcium signaling and neurotransmitter release as well as chromatin metabolism. | La protein homolog; May be involved in transcription termination by RNA polymerase III. Binds RNA and DNA. Binds to precursors of RNA polymerase III transcripts. May play a specialized role during fly development. | 0.834 |
P32 | Rho1 | FBpp0086051 | FBpp0086354 | CG6459 protein; P32 (P32) encodes an evolutionarily conserved mitochondrial protein that functions in presynaptic calcium signaling and neurotransmitter release as well as chromatin metabolism. | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | 0.504 |
P32 | Sb | FBpp0086051 | FBpp0310459 | CG6459 protein; P32 (P32) encodes an evolutionarily conserved mitochondrial protein that functions in presynaptic calcium signaling and neurotransmitter release as well as chromatin metabolism. | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | 0.528 |
Peritrophin-A | Sb | FBpp0077028 | FBpp0310459 | Peritrophin A, isoform A; Chitin binding. It is involved in the biological process described with: multicellular organism reproduction; chitin metabolic process. | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | 0.430 |
Rho1 | P32 | FBpp0086354 | FBpp0086051 | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | CG6459 protein; P32 (P32) encodes an evolutionarily conserved mitochondrial protein that functions in presynaptic calcium signaling and neurotransmitter release as well as chromatin metabolism. | 0.504 |
Rho1 | Sb | FBpp0086354 | FBpp0310459 | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | 0.495 |
Rho1 | br | FBpp0086354 | FBpp0303432 | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | Broad-complex core protein isoform 6; Broad-complex proteins are required for puffing and transcription of salivary gland late genes during metamorphosis. | 0.445 |
Sb | CG10340 | FBpp0310459 | FBpp0082803 | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | RE28913p; It is involved in the biological process described with: mitochondrial proton-transporting ATP synthase complex assembly. | 0.496 |
Sb | Cyp4c3 | FBpp0310459 | FBpp0085074 | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | Cytochrome P450 4c3; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides. | 0.497 |
Sb | La | FBpp0310459 | FBpp0080906 | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | La protein homolog; May be involved in transcription termination by RNA polymerase III. Binds RNA and DNA. Binds to precursors of RNA polymerase III transcripts. May play a specialized role during fly development. | 0.606 |
Sb | Oseg5 | FBpp0310459 | FBpp0288481 | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | Outer segment 5; It is involved in the biological process described with: non-motile cilium assembly; cilium assembly. | 0.481 |
Sb | P32 | FBpp0310459 | FBpp0086051 | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | CG6459 protein; P32 (P32) encodes an evolutionarily conserved mitochondrial protein that functions in presynaptic calcium signaling and neurotransmitter release as well as chromatin metabolism. | 0.528 |
Sb | Peritrophin-A | FBpp0310459 | FBpp0077028 | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | Peritrophin A, isoform A; Chitin binding. It is involved in the biological process described with: multicellular organism reproduction; chitin metabolic process. | 0.430 |
Sb | Rho1 | FBpp0310459 | FBpp0086354 | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | Ras-like GTP-binding protein Rho1; Has a role in regulating actin cytoskeletal organization: required during early development for proper execution of morphogenetic movements of individual cells and groups of cells important for the formation of the embryonic body plan. Plays a role in regulating dorsal closure during embryogenesis. During axis elongation, required for Rho-kinase Rok planar polarity and adherens junction localization as well as for generating a planar polarized distribution of the actin-binding protein Shrm. During embryogenesis, acts upstream of wash to regulate the d [...] | 0.495 |
Sb | br | FBpp0310459 | FBpp0303432 | Serine proteinase stubble non-catalytic chain; Hormone dependent protease required for epithelial morphogenesis, including the formation of bristles, legs, and wings. Has a dual function, detaches imaginal disk cells from extracellular matrices through its extracellular proteolytic domain and transmits an outside-to-inside signal to its intracellular domain to modify the cytoskeleton during morphogenesis; Belongs to the peptidase S1 family. | Broad-complex core protein isoform 6; Broad-complex proteins are required for puffing and transcription of salivary gland late genes during metamorphosis. | 0.539 |