STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmwProtein hemingway; Involved in assembly and/or maintenance of motile cilia. Required during spermatogenesis for axoneme elongation. Necessary for optimal function of the chordotonal (hearing) organs. (604 aa)    
Predicted Functional Partners:
CG42534
Uncharacterized protein, isoform C.
    
 
 0.810
CG7668
FI21813p1.
      
 0.790
ssp5
Short spindle 5.
   
    0.750
CG15631
Uncharacterized protein, isoform A.
   
  
 0.734
TTLL6B
Tubulin tyrosine ligase-like 6B; ATP binding; protein-glycine ligase activity; tubulin-glutamic acid ligase activity; tubulin binding. It is involved in the biological process described with: protein polyglutamylation; protein polyglycylation; microtubule cytoskeleton organization.
   
  
 0.690
CG5089
GH06435p.
   
    0.686
CG9855
FI03672p; Ubiquitin protein ligase activity; ubiquitin-protein transferase activity; zinc ion binding. It is involved in the biological process described with: protein polyubiquitination.
      
 0.679
CG13096
Ribosomal L1 domain-containing protein CG13096; RNA binding. It is involved in the biological process described with: maturation of LSU-rRNA; Belongs to the universal ribosomal protein uL1 family. Highly divergent.
      
 0.677
Dic2
Dicarboxylate carrier 2, isoform A; Belongs to the mitochondrial carrier (TC 2.A.29) family.
   
    0.666
Sdc
Syndecan (Sdc) encodes a transmembrane heparan sulfate proteoglycan. It binds to the products of sli and robo1 to regulate axon guidance at the CNS midline, and it cooperates with the product of Lar to promote synapse growth at the larval neuromuscular junction.
    
 
 0.613
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.