GEO07882p1; It is involved in the biological process described with: protein stabilization; negative regulation of apoptotic process.

Ubiquitin-60S ribosomal protein L40; [Ubiquitin]: exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is invol [...]

Ubiquitin specific protease 39; Thiol-dependent ubiquitinyl hydrolase activity; zinc ion binding; thiol-dependent ubiquitin-specific protease activity. It is involved in the biological process described with: protein deubiquitination; spliceosomal complex assembly; mRNA splicing, via spliceosome.

Protein purity of essence; Has a role in growth of the perineurial glial layer of the larval peripheral nerve. May have a role in male fertility and eye development or function. Involved in the negative regulation of the Ras/MAPK signaling pathway in the wing by acting with the E2 enzyme Unc6 and the putative E3 ligases Kcmf1 and Ufd4 to mediate the ubiquitination and proteasomal degradation of rl/MAPK.

Ubiquitin-conjugating enzyme E2-22 kDa; Catalyzes the covalent attachment of ubiquitin to other proteins.

E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to TER94/VCP recruitment for extraction and degradation of the incomplete translation product (By similarity). Belongs to the LTN1 family.

Probable E3 ubiquitin-protein ligase sinah; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. The adapter phyl is required to direct the degradation of the two isoforms of the transcriptional repressor Tramtrack (Ttk). E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It probably triggers the ubiquitin-mediated degradation of different substrates. A phyl-independent mechanism of degradation exists for [...]

Roquin, isoform A; Ubiquitin protein ligase activity; RNA binding; metal ion binding; zinc ion binding. It is involved in the biological process described with: protein polyubiquitination.

E3 ubiquitin-protein ligase hyd; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates (By similarity). Required for regulation of cell proliferation in imaginal disks and germ cells. Acts as a negative regulator of hh, ci and dpp expression in the anterior of the eye disk.