STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp12a5Probable cytochrome P450 12a5, mitochondrial; Heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen. It is involved in the biological process described with: oxidation-reduction process; Belongs to the cytochrome P450 family. (536 aa)    
Predicted Functional Partners:
Cyp12a4
Probable cytochrome P450 12a4, mitochondrial; Has a role in resistance to insecticide lufenuron, but no other insecticides.
  
  
0.659
Cyp9f3
Cyp9f3; Heme binding; iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; monooxygenase activity. It is involved in the biological process described with: oxidation-reduction process.
  
 
 0.651
CG9287
COesterase domain-containing protein.
      
 0.602
alpha-Est7
alpha-Esterase-7 (alpha-Est7) encodes a carboxylic ester hydrolase involved in insecticide tolerance, lipid metabolism and lifespan control; Belongs to the type-B carboxylesterase/lipase family.
   
  
 0.541
Cyp316a1
Probable cytochrome P450 316a1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
 
 0.538
CG9289
COesterase domain-containing protein; Carboxylic ester hydrolase activity.
      
 0.523
Cyp6w1
Probable cytochrome P450 6w1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
0.523
Cyp4p1
Cytochrome P450 4p1; May be involved in the metabolism of insect hormones and in the breakdown of synthetic insecticides.
  
 
0.514
CG3841
Carboxylic ester hydrolase activity; Belongs to the type-B carboxylesterase/lipase family.
   
  
 0.498
Cyp6d2
Cyp6d2 (Cyp6d2) encodes a member of the cytochrome P450 oxidase protein family and is involved in the detoxification of toxic compounds. Two common Cyp6d2 alleles found in many Dmel stocks result in extreme sensitivity to camptothecin.
  
 
0.492
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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