STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Surf6Surfeit locus protein 6 homolog; Involved in a nucleolar function; Belongs to the SURF6 family. (324 aa)    
Predicted Functional Partners:
ppan
Protein Peter pan; Required for initiation of larval growth and normal mitotic growth but is not absolutely required for general biosynthesis or DNA replication. Required for progression of normal oogenesis and maturation of some imaginal tissues into adult structures.
   
 
 0.995
CG1542
Probable rRNA-processing protein EBP2 homolog; Required for the processing of the 27S pre-rRNA. Belongs to the EBP2 family.
   
 
 0.988
Nnp-1
Ribosomal RNA processing protein 1 homolog; May be involved in the generation of 28S rRNA; Belongs to the RRP1 family.
   
 
 0.985
Rbm13
Protein MAK16 homolog; It is involved in the biological process described with: maturation of LSU-rRNA; maturation of 5.8S rRNA; Belongs to the MAK16 family.
   
   0.983
CG6937
RRM domain-containing protein; mRNA binding; RNA binding. It is involved in the biological process described with: maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA).
   
 
 0.982
Non1
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit (By similarity). Required for normal assembly of the mitotic spindle. May be involved in both centrosome-dependent and centrosome-independent spindle assembly programs. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
 
 0.982
CG6712
Probable ribosome production factor 1; May be required for ribosome biogenesis.
   
 
 0.981
CG3817
RRP15-like protein; It is involved in the biological process described with: maturation of 5.8S rRNA; maturation of LSU-rRNA; Belongs to the RRP15 family.
   
 
 0.978
CG11583
Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family.
   
 
 0.975
CG4364
Pescadillo homolog; Required for maturation of ribosomal RNAs and formation of the large ribosomal subunit; Belongs to the pescadillo family.
   
 
 0.962
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.