STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TotXTurandot X (TotX) encodes a protein that belongs to a class of poorly characterized secreted peptides. Some Turandot genes are expressed in response to stress in the fat body by the JAK-STAT pathway. (142 aa)    
Predicted Functional Partners:
TotC
Turandot C (TotC) encodes a protein that belongs to a class of poorly characterized secreted peptides. Some Turandot genes are expressed in response to stress in the fat body by the JAK-STAT pathway.
   
  
 0.915
TotM
Turandot M (TotM) encodes a protein that belongs to a class of poorly characterized secreted peptides. Some Turandot genes are expressed in response to stress in the fat body by the JAK-STAT pathway.
   
  
 0.913
TotA
Protein Turandot A; A humoral factor that plays a role in stress tolerance; gives increased resistance to the lethal effects of bacterial challenge and stress. Regulated by the JAK/STAT pathway and NF-KB-like Relish pathway in the fat body, upd3 in the hemocytes and Mekk1 in response to septic injury and consequent immune response. Belongs to the Turandot family.
   
  
 0.899
TotB
Turandot B (TotB) encodes a protein that belongs to a class of poorly characterized secreted peptides. Some Turandot genes are expressed in response to stress in the fat body by the JAK-STAT pathway.
   
  
 0.531
Diedel
Protein Diedel; Cytokine which promotes survival following infection by Sindbis virus by suppressing the immune deficiency pathway. Following infection by the enteropathogenic bacteria E.carotovora limits intestinal stem cells proliferation. When secreted from muscle or adipose tissue, can attenuate age-related intestinal tissue degeneration by inhibiting apoptosis ; Belongs to the Diedel family.
   
  
 0.515
CG8157
Uncharacterized protein, isoform A.
      
 0.489
su(w[a])
Protein suppressor of white apricot; Regulator of pre-mRNA splicing (and, possibly, of other RNA processing events). Regulates its own expression at the level of RNA processing.
      
 0.461
CG4293
EG:65F1.1 protein; It is involved in the biological process described with: endoplasmic reticulum to Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum.
      
 0.461
Gbp3
Growth-blocking peptide 3, isoform A; Cytokine activity. It is involved in the biological process described with: signal transduction.
      
 0.461
BomBc2
Uncharacterized protein, isoform A.
   
  
 0.448
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.