STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG5382Zinc finger protein-like 1 homolog; Zinc ion binding. It is involved in the biological process described with: dsRNA transport. (299 aa)    
Predicted Functional Partners:
CG11920
FI08810p; snoRNA binding. It is involved in the biological process described with: rRNA processing.
      
 0.602
Mgat1
Mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (Mgat1) encodes an enzyme involved in the synthesis of paucimannose N-glycans. It is required in the CNS, with involvement in locomotion, brain development and lifespan.
      
 0.570
AdSL
Adenylosuccinate Lyase (AdSL) encodes a protein that might be a lyase involved in purine nucleotide metabolic process based on orthology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
   
  
 0.569
Ostgamma
Oligosaccharide transferase gamma subunit (Ostgamma) encodes a subunit of the oligosaccharyltransferase complex involved in cell migration and cellular encapsulation response.
   
  
 0.564
CG15111
FI04476p; Acylglycerol lipase activity; lysophospholipase activity. It is involved in the biological process described with: monoacylglycerol catabolic process; phosphatidylserine catabolic process.
   
  
 0.532
Rad9
Cell cycle checkpoint control protein; Rad9 (Rad9) encodes a protein that, together with the Rad1 and Hus1-like products, forms the 9-1-1 checkpoint protein complex. This complex plays a central role in the DNA damage-induced checkpoint response.
   
  
 0.531
TM9SF3
Transmembrane 9 superfamily member; It is involved in the biological process described with: protein localization to membrane; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
      
 0.528
ND-75
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By sim [...]
 
      0.457
mfrn
Mitoferrin; Mitochondrial iron transporter that mediates iron uptake. Probably required for heme synthesis of hemoproteins and Fe-S cluster assembly; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.436
brp
Bruchpilot, isoform J; Bruchpilot (brp) encodes a cytoskeletal protein critical for structural integrity of electron-dense projection (T-bar) at pre-active zones. It contributes to Ca[2+] channel clustering, size regulation of the synaptic vesicle readily releaseable pool and anesthesia-resistant memory formation.
      
 0.426
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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