V-type proton ATPase subunit E; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

Uncharacterized protein, isoform B; Proton-transporting ATPase activity, rotational mechanism; proton-transporting ATP synthase activity, rotational mechanism. It is involved in the biological process described with: regulation of cellular pH.

ATPase H(+)-transporting accessory protein 2 C-terminal fragment; Multifunctional protein which functions as transmembrane receptor in the planar cell polarity (PCP) and is involved in the assembly of the proton-transporting vacuolar (V)-ATPase protein pump. As transmembrane receptor mediates fz/PCP signaling through interaction with fz and stabilizes asymmetric PCP domains through its interaction with stan. Also mediates Wnt/beta-cat signaling through interaction with fz/fz2. Probably by controlling the assembly of the V-ATPase pump and thus the acidification of the endo-lysosomal sys [...]

V-type proton ATPase proteolipid subunit; Vacuolar H[+] ATPase 16kD subunit 2 (Vha16-2) encodes the main subunit of the membrane-embedded V0 sector of the vacuolar-ATPase, which is responsible for acidification of the endo-lysosomal lumen and other cellular compartment. As part of the V-ATPase, the product of Vha16-2 supports membrane trafficking, protein degradation and multiple associated signaling pathways, such as mTor, Wnt and Notch.

Vacuolar H[+] ATPase 100kD subunit 1 (Vha100-1) encodes a subunit of the V0 domain of V-ATPase, which acidifies autophagosomes and lysosomes in neurons. The product of Vha100-1 is involved in autophagosome maturation, tracheal branching and eye development.

V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates the ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity).

Vacuolar H[+] ATPase 16kD subunit 1 (Vha16-1) encodes the proteolipid component of V-ATPase, which is a multi-functional channel protein. It contributes to vesicle-membrane fusion, hydrophilic molecule transport and intercellular communication.

Vacuolar H[+] ATPase 68 kDa subunit 2 (Vha68-2) encodes a component of the V1 subunit of the vacuolar ATPase, which acidifies endosomal compartments including the lysosome and influences the activity of several signaling pathways.

Vacuolar H[+] ATPase 68kD subunit 3; ATP binding; proton-transporting ATPase activity, rotational mechanism. It is involved in the biological process described with: proton transmembrane transport; ATP metabolic process.