STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CG10177Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: Golgi organization; protein phosphorylation; mitotic DNA damage checkpoint; negative regulation of cell size; signal transduction in response to DNA damage. (411 aa)    
Predicted Functional Partners:
CG7848
GH17657p; Malate dehydrogenase (decarboxylating) (NAD+) activity; malate dehydrogenase (decarboxylating) (NADP+) activity; NAD binding; malic enzyme activity. It is involved in the biological process described with: oxidation-reduction process; pyruvate metabolic process; malate metabolic process.
   
    0.999
DCX-EMAP
Echinoderm microtubule-associated protein-like CG42247; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
    
 
 0.811
Prosalpha6T
Proteasome subunit alpha type; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1A family.
   
  
 0.767
CG13544
AT20903p.
   
 
 0.764
CG2577
CG2577-PA; Protein serine/threonine kinase activity; ATP binding. It is involved in the biological process described with: peptidyl-serine phosphorylation; Wnt signaling pathway.
  
  
 0.762
Hsp60B
60 kDa heat shock protein homolog 1, mitochondrial; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. Belongs to the chaperonin (HSP60) family.
   
  
 0.754
CG4661
Uncharacterized protein; It is involved in the biological process described with: ubiquitin-dependent protein catabolic process.
   
    0.750
CG7557
GH07076p.
   
    0.750
CG9389
GH15479p; Inositol monophosphate 1-phosphatase activity. It is involved in the biological process described with: inositol metabolic process; signal transduction; inositol phosphate dephosphorylation; phosphatidylinositol phosphorylation.
   
    0.750
CG14448
AT10852p.
   
    0.750
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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